Maciulaitis Tomas, Rimdeikaite Monika, Gudaviciene Daiva, Jakutis Nerijus
Faculty of Medicine, Institute of Clinical Medicine, Clinic of Rheumatology, Orthopedics, Traumatology and Reconstructive Surgery, Vilnius University, Vilnius, Lithuania.
Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Front Surg. 2025 Jun 18;12:1617716. doi: 10.3389/fsurg.2025.1617716. eCollection 2025.
Phyllodes tumours are rare fibroepithelial neoplasms, accounting for less than 1 percent of all breast malignancies, with most cases occurring in women between 40 and 50 years of age. Their occurrence in the paediatric population is highly uncommon, representing less than 10 percent of all phyllodes tumour cases. Due to overlapping clinical and radiological features, these tumours often pose diagnostic challenges, as they are frequently misdiagnosed as fibroadenomas. In younger patients, additional complexities arise from ongoing breast development and the need to minimize long-term aesthetic and functional impact.
A case report was conducted detailing the clinical presentation, imaging findings, histopathological evaluation, and surgical management of a benign phyllodes tumour in a paediatric female patient.
The patient presented with a rapidly growing breast mass, initially suspected to be a fibroadenoma. Surgical excision was performed, and histopathological examination confirmed a benign phyllodes tumour. There were no postoperative complications or recurrence at follow-up.
This case highlights the diagnostic and therapeutic challenges specific to paediatric phyllodes tumours. Given their rarity and potential for misdiagnosis, surgical excision followed by histological evaluation remains crucial for accurate diagnosis. Although treatment principles are generally aligned with adult protocols, adolescents management must also consider breast development and requires a more nuanced surgical approach. Balancing oncological safety with the preservation of breast contour and function introduces unique complexities in this age group. Reporting such cases contributes to the limited literature on juvenile phyllodes tumours and raises awareness of their distinct clinical considerations.
叶状肿瘤是一种罕见的纤维上皮性肿瘤,占所有乳腺恶性肿瘤的比例不到1%,大多数病例发生在40至50岁的女性中。它们在儿科人群中的发生极为罕见,占所有叶状肿瘤病例的比例不到10%。由于临床和影像学特征重叠,这些肿瘤常常带来诊断挑战,因为它们经常被误诊为纤维腺瘤。在年轻患者中,由于乳房仍在发育以及需要尽量减少对长期美观和功能的影响,情况更加复杂。
进行了一例病例报告,详细描述了一名儿科女性患者的良性叶状肿瘤的临床表现、影像学检查结果、组织病理学评估和手术治疗情况。
该患者表现为乳房肿块迅速增大,最初怀疑是纤维腺瘤。进行了手术切除,组织病理学检查证实为良性叶状肿瘤。随访期间无术后并发症或复发。
本病例突出了儿科叶状肿瘤特有的诊断和治疗挑战。鉴于其罕见性和误诊可能性,手术切除后进行组织学评估对于准确诊断仍然至关重要。尽管治疗原则通常与成人方案一致,但青少年患者的管理还必须考虑乳房发育情况,需要更细致入微的手术方法。在这个年龄组中,平衡肿瘤学安全性与保留乳房外形和功能带来了独特的复杂性。报告此类病例有助于丰富关于青少年叶状肿瘤的有限文献,并提高对其独特临床考量的认识。