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一例肾移植受者延迟性难治性腹壁脓肿病例

A Case of Delayed Refractory Abdominal Wall Abscess in a Kidney Transplant Recipient.

作者信息

Sakurai Hisashi, Okamoto Teppei, Hamaya Tomoko, Kodama Hirotake, Fujita Naoki, Yamamoto Hayato, Mori Kazuyuki, Fujita Takeshi, Imai Atushi, Murakami Reiichi, Tomita Hirofumi, Hatakeyama Shingo

机构信息

Department of Urology Hirosaki University School of Medicine Aomori Japan.

Department of Cardiology and Nephrology Hirosaki University School of Medicine Aomori Japan.

出版信息

IJU Case Rep. 2025 May 9;8(4):369-372. doi: 10.1002/iju5.70042. eCollection 2025 Jul.

DOI:10.1002/iju5.70042
PMID:40607459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12212928/
Abstract

INTRODUCTION

(), a rare non-tuberculous mycobacterium (NTM), can cause infections in immunocompromised patients, including kidney transplant recipients. We present a case of an abdominal wall abscess caused by following a living donor kidney transplant.

CASE PRESENTATION

A 58-year-old woman, post-ABO-incompatible kidney transplant, developed an abscess at the site of a removed peritoneal dialysis catheter. Initial antibiotics were ineffective, and pus cultures identified . Surgical drainage and levofloxacin-linezolid therapy controlled the infection temporarily. Despite clinical improvement, the abscess recurred 30 days post-discharge, which required repeated antibiotic use and adjustments to immunosuppression. Reducing mycophenolate mofetil while maintaining tacrolimus stabilized the infection, and prophylactic levofloxacin was continued post-discharge to prevent relapse.

CONCLUSION

Effective infection control requires careful immunosuppressive adjustment and long-term antibiotic use to balance graft preservation with infection risk.

摘要

引言

()是一种罕见的非结核分枝杆菌(NTM),可导致免疫功能低下患者感染,包括肾移植受者。我们报告一例活体供肾肾移植后由()引起的腹壁脓肿病例。

病例介绍

一名58岁女性,ABO血型不相容肾移植术后,在拔除腹膜透析导管部位出现脓肿。初始抗生素治疗无效,脓液培养鉴定出()。手术引流及左氧氟沙星-利奈唑胺治疗暂时控制了感染。尽管临床症状改善,但出院后30天脓肿复发,需要重复使用抗生素并调整免疫抑制方案。减少霉酚酸酯用量同时维持他克莫司用量使感染得到控制,出院后继续使用预防性左氧氟沙星以防止复发。

结论

有效的感染控制需要仔细调整免疫抑制方案并长期使用抗生素,以平衡移植肾保存与感染风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/3d8a4a3f4dcf/IJU5-8-369-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/ea1e53aac450/IJU5-8-369-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/9e593b8308b5/IJU5-8-369-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/e9f78452f7d6/IJU5-8-369-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/3d8a4a3f4dcf/IJU5-8-369-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/ea1e53aac450/IJU5-8-369-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/9e593b8308b5/IJU5-8-369-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/e9f78452f7d6/IJU5-8-369-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d393/12212928/3d8a4a3f4dcf/IJU5-8-369-g002.jpg

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本文引用的文献

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Safety and Efficacy of a Preemptive Mycophenolate Mofetil Dose Reduction Strategy in Kidney Transplant Recipients.肾移植受者中霉酚酸酯预先减量策略的安全性和有效性
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A Ventral Hernia-repair-related Mesh Infection Treated with NPWT without Mesh Removal.
经负压伤口治疗(NPWT)处理且未移除补片的腹疝修补相关补片感染
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