Siegle Cristhina Bonilha Huster, Maciel Flaviana Kelly de Lima, Castro Pedro Claudio Gonsales de, Tamashiro Daniel Seiei Uehara, Sá Cristina Dos Santos Cardoso de
Universidade Federal de São Paulo - Santos (SP), Brazil.
Faculdade de Medicina da Universidade de São Paulo - São Paulo (SP), Brazil.
Rev Paul Pediatr. 2025 Jun 27;43:e2024243. doi: 10.1590/1984-0462/2025/43/2024243. eCollection 2025.
To verify whether there is an increase in the center of pressure (COP) displacement velocity and area in individuals with Duchenne muscular dystrophy (DMD) in Vignos stages 2 and 3, assessed under different sensory conditions; to verify whether COP displacement velocity and area increase within the same Vignos stage with changes in sensory conditions during postural control assessment.
A cross-sectional study was conducted with individuals with DMD in Vignos stages 2 and 3, aged between 7 and 19 years old (mean 9.58, SD±3.22). Postural control was assessed using the Wii Balance Board and a modified sensory organization test. COP displacement velocity and area were recorded. Independent samples t-tests were performed to compare the average values of these variables between Vignos 2 and 3 under each sensory condition and within the same Vignos stage across different sensory conditions.
No significant difference were found in any analyzed variable between Vignos 2 and 3. However. A significant difference was observed when comparing sensory condition 1 with condition 4, within the same disease stage.
Despite the decrease in muscle strength from Vignos 2 to 3, participants were able to employ motor strategies to maintain postural control. However, postural control performance significantly worsens with changes in sensory conditions within the same Vignos stage.
验证在不同感觉条件下评估的、处于维格诺斯（Vignos）2期和3期的杜氏肌营养不良症（DMD）患者的压力中心（COP）位移速度和面积是否增加；验证在姿势控制评估期间，随着感觉条件的变化，同一维格诺斯阶段内COP位移速度和面积是否增加。
对年龄在7至19岁（平均9.58，标准差±3.22）、处于维格诺斯2期和3期的DMD患者进行了一项横断面研究。使用Wii平衡板和改良的感觉组织测试评估姿势控制。记录COP位移速度和面积。进行独立样本t检验，以比较在每种感觉条件下维格诺斯2期和3期之间以及在同一维格诺斯阶段不同感觉条件下这些变量的平均值。
在维格诺斯2期和3期之间，任何分析变量均未发现显著差异。然而，在同一疾病阶段，比较感觉条件1和条件4时观察到显著差异。
尽管从维格诺斯2期到3期肌肉力量有所下降，但参与者能够采用运动策略来维持姿势控制。然而，在同一维格诺斯阶段，随着感觉条件的变化，姿势控制表现显著恶化。
