Karakök Taliha, Bakkaloğlu Zekiye, Şimşek Hüsniye, Numanoğlu Çevik Yasemin, Beyaz Elif
İnfectious Disease and Clinical Microbiology Department, Fatsa State Hospital, Fatsa, Ordu, Türkiye.
National Antimicrobial Resistance Surveillance Laboratory, Department of Microbiology Reference Laboratories and Biological Products, General Directorate of Public Health, Ankara, Türkiye.
J Infect Dev Ctries. 2025 Jun 30;19(6):990-996. doi: 10.3855/jidc.20190.
The aim of this study was to report a 9-case Myroides odoratimimus outbreak in the intensive care units (ICUs) of a secondary care hospital.
The hospital laboratory recorded several consecutive detections of Myroides spp. in urine samples in March 2023. Consequently, an outbreak investigation was initiated. Epidemiological data of each patient was collected to identify the cause of the outbreak.
All patients were followed up in the ICU and all growths were found to be in urinary catheters. None of the patients had clinical symptoms of urinary tract infection. Outbreak investigation revealed that urine bottles, which should be separate for each ICU patient, were in fact used for all patients. Environmental sampling of surfaces was not performed. No clustering was observed in terms of patients regarding follow-up doctors and staff. There was no mortality among these patients during the outbreak. All strains identified as Myroides spp. in the hospital laboratory were identified as Myroides odoratimimus with matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF-MS). Pulsed-field gel electrophoresis (PFGE) revealed that there were 3 PFGE groups. The clustering rate was 88.8%. When the similarity ratio between PFGE profiles was > 85, one of the 9 strains showed a unique profile; while the remaining 8 strains were classified into 2 epidemiologically related groups.
Myroides spp. represents a new threat with a broad antimicrobial resistance profile, and the potential to cause epidemics across a wide clinical spectrum from colonization to lethal infection, particularly in ICU patients.
本研究旨在报告一家二级护理医院重症监护病房（ICU）发生的9例气味类鼻疽杆菌暴发事件。
医院实验室在2023年3月记录到尿液样本中连续多次检测到类鼻疽杆菌属。因此，启动了一次暴发调查。收集了每位患者的流行病学数据以确定暴发原因。
所有患者均在ICU接受随访，所有培养物均在导尿管中发现。所有患者均无尿路感染的临床症状。暴发调查显示，本应为每位ICU患者单独使用的尿瓶实际上被所有患者共用。未对环境表面进行采样。在随访医生和工作人员方面，患者之间未观察到聚集现象。暴发期间这些患者均无死亡。医院实验室鉴定为类鼻疽杆菌属的所有菌株经基质辅助激光解吸电离飞行时间质谱（MALDI-TOF-MS）鉴定为气味类鼻疽杆菌。脉冲场凝胶电泳（PFGE）显示有3个PFGE组。聚类率为88.8%。当PFGE图谱之间的相似率>85时，9株菌株中的1株显示出独特的图谱；而其余8株菌株分为2个流行病学相关组。
类鼻疽杆菌属是一种新的威胁，具有广泛的抗菌药物耐药谱，有在从定植到致死性感染的广泛临床范围内引起流行的潜力，尤其是在ICU患者中。
