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教育作为秘鲁成人新冠疫苗接种中种族差异的调节因素

Education as a mediator of ethnic disparities in adult COVID-19 vaccination in Peru.

作者信息

Al-Kassab-Córdova Ali, Mezones-Holguín Edward, Kaufman Jay S

机构信息

Centro de Excelencia en Investigaciones Económicas y Sociales en Salud, Universidad San Ignacio de Loyola, Lima, Peru.

Centro de Excelencia en Investigaciones Económicas y Sociales en Salud, Universidad San Ignacio de Loyola, Lima, Peru; Epignosis Solutions, Piura, Peru.

出版信息

Vaccine. 2025 Jul 2;61:127436. doi: 10.1016/j.vaccine.2025.127436.

Abstract

BACKGROUND

COVID-19 vaccines have saved millions of lives, although access is still unequal and subject to several underlying factors. This study aimed to evaluate the mediating role of educational level on ethnic disparities in COVID-19 vaccination status in Peru.

METHODS

We performed a cross-sectional study based on Peru's 2022 National Household Survey. Vaccination status was defined as receiving 'zero doses' versus 'one or more doses'. Education level was categorized as low education (none or primary) and high education (secondary and higher). A 4-way decomposition analysis using interventional analogues was performed to assess the mediating and moderating roles of educational attainment in the association between self-reported ethnicity (Indigenous vs Mestizos, and Afro-Peruvian vs Mestizos) and COVID-19 vaccination status.

RESULTS

A total of 51,505 adults were included. Mestizo was self-reported as the most common ethnicity (57.9%), followed by Indigenous (34.1%) and Afro-Peruvian (8.0%). Indigenous and Afro-Peruvians had an absolute risk of not receiving any COVID-19 vaccination that was 14 and 28 percentage points higher, respectively, in comparison to Mestizo ethnicity. About 30% of the observed disparity was mediated through education level in both ethnic contrasts. The contributions of reference and mediated interactions were negligible, indicating an absence of intersectionality in this disparity.

CONCLUSION

The ethnic disparity in adult COVID-19 vaccination coverage between Afro-Peruvians and Mestizos is twice as large as the disparity between Indigenous people and Mestizos. Increasing education levels for minority Peruvians would substantially diminish ethnic disparities in vaccination coverage.

摘要

背景

新冠疫苗挽救了数百万人的生命,尽管疫苗接种机会仍然不平等,且受到多种潜在因素的影响。本研究旨在评估教育水平在秘鲁新冠疫苗接种状况的种族差异中所起的中介作用。

方法

我们基于秘鲁2022年全国住户调查开展了一项横断面研究。疫苗接种状况定义为“未接种”与“接种一剂或多剂”。教育水平分为低教育水平(无教育或小学教育)和高教育水平(中学及以上教育)。使用干预模拟进行了四向分解分析,以评估教育程度在自我报告的种族(原住民与混血儿,以及非裔秘鲁人与混血儿)与新冠疫苗接种状况之间的关联中所起的中介和调节作用。

结果

共纳入51,505名成年人。自我报告中最常见的种族是混血儿(57.9%),其次是原住民(34.1%)和非裔秘鲁人(8.0%)。与混血儿相比,原住民和非裔秘鲁人未接种任何新冠疫苗的绝对风险分别高出14个和28个百分点。在两种种族对比中,约30%的观察到的差异是通过教育水平介导的。参考和介导的相互作用的贡献可忽略不计,表明这种差异不存在交叉性。

结论

非裔秘鲁人与混血儿之间成人新冠疫苗接种覆盖率的种族差异是原住民与混血儿之间差异的两倍。提高秘鲁少数族裔的教育水平将大幅减少疫苗接种覆盖率的种族差异。

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