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[免疫与癌症:对携带同基因肿瘤动物的淋巴细胞细胞毒性活性的抑制作用]

[Immunity and cancer: suppressor effect on the cytotoxic activity of lymphoid cells from animals carrying syngeneic tumors].

作者信息

Schaaf-Lafontaine N, Firket H

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 May 2;284(17):1741-3.

PMID:406097
Abstract

When it is tested in vitro, the cytotoxic action of lymphocytes from mice bearing a syngeneic tumour (T2) vary with the age of the graft. At a time when it is very low, the lymphoid cells are cultivated for 3 days and then can be fractionated in two subpopulations on a glass bead column: a cytotoxic "non adherent" group of cells and an "adherent" group that inhibits the activity of the first group when it is added to it.

摘要

当在体外进行测试时,携带同基因肿瘤(T2)的小鼠淋巴细胞的细胞毒性作用会随移植物的年龄而变化。在其活性非常低的时候,将淋巴细胞培养3天,然后可以在玻璃珠柱上分离为两个亚群:具有细胞毒性的“非贴壁”细胞群和“贴壁”细胞群,当将“贴壁”细胞群加入到“非贴壁”细胞群中时,会抑制其活性。

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