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Is immune effector cell-associated enterocolitis a CAR T-cell lymphoproliferative disorder?

作者信息

Somay Kayra, Azakli Hulya, Chahine Joeffrey J, Loughney Thomas M, Ozdemirli Metin

机构信息

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

Pathology, MedStar Georgetown University Hospital, Washington, DC, USA.

出版信息

Blood Cancer J. 2025 Jul 3;15(1):117. doi: 10.1038/s41408-025-01319-4.

DOI:10.1038/s41408-025-01319-4
PMID:40610397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12229613/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6ba/12229613/36034369b81d/41408_2025_1319_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6ba/12229613/36034369b81d/41408_2025_1319_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6ba/12229613/36034369b81d/41408_2025_1319_Fig1_HTML.jpg

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Nat Med. 2025 Apr;31(4):1145-1153. doi: 10.1038/s41591-025-03499-9. Epub 2025 Feb 21.
2
CD4+ T-Cell Lymphoma Harboring a Chimeric Antigen Receptor Integration in .携带嵌合抗原受体整合的CD4 + T细胞淋巴瘤于……
N Engl J Med. 2025 Feb 6;392(6):577-583. doi: 10.1056/NEJMoa2411507.
3
Immune effector cell-associated enterocolitis following chimeric antigen receptor T-cell therapy in multiple myeloma.
嵌合抗原受体 T 细胞疗法治疗多发性骨髓瘤后免疫效应细胞相关肠炎。
Blood Cancer J. 2024 Oct 16;14(1):180. doi: 10.1038/s41408-024-01167-8.
4
Indolent CD4+ CAR T-Cell Lymphoma after Cilta-cel CAR T-Cell Therapy.西达基奥仑赛（cilta-cel）CAR-T 细胞治疗后惰性 CD4+ CAR T 细胞淋巴瘤。
N Engl J Med. 2024 Jun 13;390(22):2074-2082. doi: 10.1056/NEJMoa2401530.
5
Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy.CAR T 细胞治疗后第二肿瘤和 T 细胞淋巴瘤的风险。
N Engl J Med. 2024 Jun 13;390(22):2047-2060. doi: 10.1056/NEJMoa2401361.
6
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease.麸质诱导乳糜泻中天然记忆性αβ和γδ上皮内 T 细胞的快速重编程，从而诱导细胞毒性。
Sci Immunol. 2023 Jul 21;8(85):eadf4312. doi: 10.1126/sciimmunol.adf4312. Epub 2023 Jul 14.
7
Analysis of Circulating Food Antigen-Specific T-Cells in Celiac Disease and Inflammatory Bowel Disease.分析乳糜泻和炎症性肠病患者循环食物抗原特异性 T 细胞。
Int J Mol Sci. 2023 May 2;24(9):8153. doi: 10.3390/ijms24098153.
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