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使用度量优化知识蒸馏对医学超声图像进行去斑处理。

De-speckling of medical ultrasound image using metric-optimized knowledge distillation.

作者信息

Khalifa Mostafa, Hamza Hanaa M, Hosny Khalid M

机构信息

Department of Information Technology, Faculty of Computers and Informatics, Zagazig University, Zagazig, 44519, Egypt.

出版信息

Sci Rep. 2025 Jul 3;15(1):23703. doi: 10.1038/s41598-025-07115-1.

DOI:10.1038/s41598-025-07115-1
PMID:40610463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12229328/
Abstract

Ultrasound imaging provides real-time views of internal organs, which are essential for accurate diagnosis and treatment. However, speckle noise, caused by wave interactions with tissues, creates a grainy texture that hides crucial details. This noise varies with image intensity, which limits the effectiveness of traditional denoising methods. We introduce the Metric-Optimized Knowledge Distillation (MK) model, a deep-learning approach that utilizes Knowledge Distillation (KD) for denoising ultrasound images. Our method transfers knowledge from a high-performing teacher network to a smaller student network designed for this task. By leveraging KD, the model removes speckle noise while preserving key anatomical details needed for accurate diagnosis. A key innovation of our paper is the metric-guided training strategy. We achieve this by repeatedly computing evaluation metrics used to assess our model. Incorporating them into the loss function enables the model to reduce noise and enhance image quality optimally. We evaluate our proposed method against state-of-the-art despeckling techniques, including DNCNN and other recent models. The results demonstrate that our approach performs superior noise reduction and image quality preservation, making it a valuable tool for enhancing the diagnostic utility of ultrasound images.

摘要

超声成像可提供内部器官的实时视图,这对于准确诊断和治疗至关重要。然而,由波与组织相互作用引起的斑点噪声会产生一种颗粒状纹理,掩盖了关键细节。这种噪声随图像强度而变化,这限制了传统去噪方法的有效性。我们引入了度量优化知识蒸馏(MK)模型,这是一种利用知识蒸馏(KD)对超声图像进行去噪的深度学习方法。我们的方法将知识从高性能的教师网络转移到为该任务设计的较小的学生网络。通过利用KD,该模型在去除斑点噪声的同时保留了准确诊断所需的关键解剖细节。我们论文的一个关键创新是度量引导训练策略。我们通过反复计算用于评估我们模型的评估指标来实现这一点。将它们纳入损失函数使模型能够最佳地降低噪声并提高图像质量。我们将我们提出的方法与包括DNCNN和其他近期模型在内的最先进的去噪技术进行了评估。结果表明,我们的方法在降噪和图像质量保留方面表现出色,使其成为提高超声图像诊断效用的有价值工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/031eb6ea74f7/41598_2025_7115_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/0a6d80ca6f48/41598_2025_7115_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/daadbbdfb63b/41598_2025_7115_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/8689edbc933a/41598_2025_7115_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/7671e9aa87ef/41598_2025_7115_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/031eb6ea74f7/41598_2025_7115_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/0a6d80ca6f48/41598_2025_7115_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/daadbbdfb63b/41598_2025_7115_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/8689edbc933a/41598_2025_7115_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/7671e9aa87ef/41598_2025_7115_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c6/12229328/031eb6ea74f7/41598_2025_7115_Fig7_HTML.jpg

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2
Broad learning solution for rapid diagnosis of COVID-19.用于快速诊断新冠病毒病的广泛学习解决方案。
Biomed Signal Process Control. 2023 May;83:104724. doi: 10.1016/j.bspc.2023.104724. Epub 2023 Feb 17.
3
Ultrasound Speckle Reduction Using Wavelet-Based Generative Adversarial Network.基于小波生成对抗网络的超声散斑减少。
IEEE J Biomed Health Inform. 2022 Jul;26(7):3080-3091. doi: 10.1109/JBHI.2022.3144628. Epub 2022 Jul 1.
4
Evaluation of target autocrop function in nasopharyngeal carcinoma SIB IMRT plan.评估鼻咽癌调强放疗计划中的靶区自动适形功能。
Phys Eng Sci Med. 2022 Mar;45(1):97-105. doi: 10.1007/s13246-021-01082-3. Epub 2021 Nov 30.
5
3-D Gabor-based anisotropic diffusion for speckle noise suppression in dynamic ultrasound images.基于 3-D Gabor 滤波器的各向异性扩散法用于动态超声图像的散斑噪声抑制。
Phys Eng Sci Med. 2021 Mar;44(1):207-219. doi: 10.1007/s13246-020-00969-x. Epub 2021 Jan 26.
6
Improved non-local self-similarity measures for effective speckle noise reduction in ultrasound images.改进的非局部自相似性度量在超声图像中的有效散斑噪声降低。
Comput Methods Programs Biomed. 2020 Nov;196:105670. doi: 10.1016/j.cmpb.2020.105670. Epub 2020 Jul 21.
7
Dataset of breast ultrasound images.乳腺超声图像数据集。
Data Brief. 2019 Nov 21;28:104863. doi: 10.1016/j.dib.2019.104863. eCollection 2020 Feb.
8
A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma.一种基因工程 miRNA-34a 前药在骨肉瘤犬模型中显示出抗肿瘤活性。
PLoS One. 2018 Dec 31;13(12):e0209941. doi: 10.1371/journal.pone.0209941. eCollection 2018.
9
Topic-Oriented Image Captioning Based on Order-Embedding.基于序嵌入的主题导向图像字幕生成
IEEE Trans Image Process. 2019 Jun;28(6):2743-2754. doi: 10.1109/TIP.2018.2889922. Epub 2018 Dec 27.
10
Personalized Models for Injected Activity Levels in SPECT Myocardial Perfusion Imaging.个性化 SPECT 心肌灌注成像注射活动水平模型。
IEEE Trans Med Imaging. 2019 Jun;38(6):1466-1476. doi: 10.1109/TMI.2018.2885319. Epub 2018 Dec 6.