巨球蛋白血症患者的临床及实验室检查结果与生存情况的关系
The relation of clinical and laboratory findings to the survival of patients with macroglobulinaemia.
作者信息
Carter P, Koval J J, Hobbs J R
出版信息
Clin Exp Immunol. 1977 May;28(2):241-9.
The relation of clinical and laboratory findings at the time clinical presentation to subsequent survival was investigated in 204 patients with macroglobulinaemia. It was found that the ten following clinical and laboratory parameters were of prognostic significance and a further twelve were not. The best prognoses were found amongst male patients, patients aged 50-69 years and those with serum IgM paraprotein concentrations of 20-39 g/1, type lambda paraproteins, no Bence-Jones proteinuria or cryoglobulinaemia, only one paraprotein, serum cold haemagglutinin activity, serum albumin above 40 g/1 and serum urea below 10 mmol/1.
对204例巨球蛋白血症患者在临床表现时的临床和实验室检查结果与后续生存情况的关系进行了研究。发现以下十个临床和实验室参数具有预后意义，另外十二个则没有。预后最好的是男性患者、年龄在50 - 69岁之间的患者、血清IgM副蛋白浓度为20 - 39 g/1的患者、λ型副蛋白患者、无本周氏蛋白尿或冷球蛋白血症的患者、仅有一种副蛋白的患者、血清冷凝集素活性、血清白蛋白高于40 g/1以及血清尿素低于10 mmol/1的患者。
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