Feng Ge-Hui, Liu Min, Chen Yun-Shan, Wang Yi-Fei, Zhao Ke-Hao, Huang Mao-Ting, Yi Wen-Ting, Zhao Ling, Zeng Ying
Department of International and Humanistic Nursing, Hunan Science Popularization Education Base, School of Nursing, Hengyang Medical School, University of South China, Hengyang, China.
The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, China.
BMC Public Health. 2025 Jul 3;25(1):2346. doi: 10.1186/s12889-025-23582-7.
Liver cancer remains a global public health threat, especially in Asia. Early detection through screening is crucial for improving survival rates in high-risk populations for liver cancer, however screening remains underutilized in clinical practice and inadequately addressed in China.
To explore the self-reported knowledge, attitudes, and practice patterns related to liver cancer screening among high-risk populations in China.
This cross-sectional study recruited high-risk individuals for liver cancer from multiple districts in Hunan Province, China. Of 1,600 eligible individuals invited, 1,401 completed the survey (response rate: 87.56%). Data were collected through anonymous questionnaires and analyzed from March to September 2024. The linear regression model was applied to measure the influencing factors associated with liver cancer screening practice. Associations between knowledge/attitudes and screening practices were assessed using the χ test or the Fisher exact test.
The study population (N = 1,401) comprised 679 (48.5%) males and 722 (51.5%) females. Only 680 participants (48.5%) reported previous liver cancer screening. Knowledge assessment revealed that 745 participants (53.2%) demonstrated fair-level knowledge, while 579 (41.3%) showed low-level knowledge. Most participants (1,077, 76.9%) exhibited positive attitudes toward screening, scoring above 50 points. Statistical analysis revealed a significant association between attitudes and screening practices (P < 0.001), while knowledge levels showed no correlation with screening practices (P = 0.696).
This study reveals significant knowledge deficits regarding liver cancer screening among high-risk populations in China, which correlates with their attitudes and screening practices. These findings emphasize the need for targeted educational programs to enhance knowledge and improve screening participation among high-risk populations.
肝癌仍然是全球公共卫生威胁，尤其是在亚洲。通过筛查进行早期检测对于提高肝癌高危人群的生存率至关重要，然而，筛查在临床实践中的应用仍然不足，在中国也未得到充分解决。
探讨中国高危人群中与肝癌筛查相关的自我报告知识、态度和实践模式。
这项横断面研究从中国湖南省的多个地区招募了肝癌高危个体。在邀请的1600名符合条件的个体中，1401人完成了调查（应答率：87.56%）。数据通过匿名问卷收集，并于2024年3月至9月进行分析。应用线性回归模型来衡量与肝癌筛查实践相关的影响因素。使用χ检验或Fisher精确检验评估知识/态度与筛查实践之间的关联。
研究人群（N = 1401）包括679名（48.5%）男性和722名（51.5%）女性。只有680名参与者（48.5%）报告曾进行过肝癌筛查。知识评估显示，745名参与者（53.2%）表现出中等水平的知识，而579名（41.3%）表现出低水平的知识。大多数参与者（1077名，76.9%）对筛查持积极态度，得分高于50分。统计分析显示态度与筛查实践之间存在显著关联（P < 0.001），而知识水平与筛查实践无相关性（P = 0.696）。
本研究揭示了中国高危人群在肝癌筛查方面存在显著的知识缺陷，这与他们的态度和筛查实践相关。这些发现强调需要开展有针对性的教育项目，以增强知识并提高高危人群的筛查参与度。
