Suppr超能文献

入住资源匮乏的混合型重症监护病房的外科患者死亡率相关因素:一项横断面研究

Factors associated with mortality in surgical patients admitted to a low-resource mixed intensive care unit: a cross-sectional study.

作者信息

Bake Jacques Fadhili, Phalek Kambere Mukama, Kigayi Jean-Pierre Mumbere, Claude Kasereka Masumbuko

机构信息

HEAL AFRICA Hospital, Goma, Democratic Republic of the Congo.

Surgery Department, University of Goma, Goma, Democratic Republic of the Congo.

出版信息

BMC Surg. 2025 Jul 3;25(1):269. doi: 10.1186/s12893-025-03031-3.

Abstract

BACKGROUND

Providing critical care is essential for improving health outcomes, particularly in low-resource settings such as the Democratic Republic of the Congo (DRC). However, there is a significant lack of data regarding the management and outcomes of critically ill surgical patients in this region. This study aimed to investigate the factors associated with mortality among surgical patients admitted to the intensive care unit (ICU) at HEAL Africa Hospital in eastern DRC.

METHODS

This retrospective cross-sectional study analyzed data from surgical patients admitted to the ICU between January 2021 and June 2023. Information was extracted from the ICU registry, including demographics, reasons for admission, management details, length of stay, and mortality rates. Categorical data were presented as frequencies, and logistic regression was used, with a p-value of less than 0.05 considered significant.

RESULTS

Out of 807 patients admitted to the ICU, 368 were surgical patients (43.12%). The cohort had a male predominance (1.6:1) with a median age of 31 years. The primary reason for admission was postoperative monitoring (57.2%). The overall mortality rate was 21.3%. Univariate analysis identified statistically significant risk factors for increased mortality: male sex (p = 0.004), age (p = 0.0409), need for mechanical ventilation (p < 0.0001), involvement in neurosurgery (p = 0.03), and non-operative management (p < 0.0001). Multivariate analysis confirmed that the need for mechanical ventilation (p < 0.0001) and the non-operative management (p < 0.0001) was significantly associated with increased mortality.

CONCLUSION

The burden of surgical critically ill patients in eastern DRC is substantial. Non-operative management and the requirement for mechanical ventilation were identified as factors influencing mortality among these patients. To tackle this pressing issue, it is essential to enhance critical care protocols, invest in the training of healthcare professionals, and allocate resources effectively.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

提供重症护理对于改善健康结局至关重要,尤其是在刚果民主共和国(DRC)等资源匮乏地区。然而,该地区关于重症外科患者的管理和结局的数据严重不足。本研究旨在调查刚果民主共和国东部HEAL非洲医院重症监护病房(ICU)收治的外科患者的死亡相关因素。

方法

这项回顾性横断面研究分析了2021年1月至2023年6月期间入住ICU的外科患者的数据。信息从ICU登记册中提取,包括人口统计学、入院原因、管理细节、住院时间和死亡率。分类数据以频率表示,并使用逻辑回归分析,p值小于0.05被认为具有统计学意义。

结果

在807名入住ICU的患者中,368名是外科患者(43.12%)。该队列男性居多(1.6:1),中位年龄为31岁。入院的主要原因是术后监测(57.2%)。总体死亡率为21.3%。单因素分析确定了死亡率增加的统计学显著风险因素:男性(p = 0.004)、年龄(p = 0.0409)、需要机械通气(p < 0.0001)、涉及神经外科手术(p = 0.03)和非手术治疗(p < 0.0001)。多因素分析证实,需要机械通气(p < 0.0001)和非手术治疗(p < 0.0001)与死亡率增加显著相关。

结论

刚果民主共和国东部外科重症患者的负担很重。非手术治疗和机械通气需求被确定为影响这些患者死亡率的因素。为解决这一紧迫问题,加强重症护理方案、投资于医疗专业人员培训并有效分配资源至关重要。

临床试验编号

不适用。

相似文献

6
Prescribed hypocaloric nutrition support for critically-ill adults.为重症成年患者开具低热量营养支持方案。
Cochrane Database Syst Rev. 2018 Jun 4;6(6):CD007867. doi: 10.1002/14651858.CD007867.pub2.
10
Early versus late tracheostomy in critically ill COVID-19 patients.危重症 COVID-19 患者的早期与晚期气管切开术。
Cochrane Database Syst Rev. 2023 Nov 20;11(11):CD015532. doi: 10.1002/14651858.CD015532.

本文引用的文献

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验