Department of Anesthesia, College of Medicine and Health Sciences, Injibara University, Injibara, Ethiopia.
Department of Anesthesia, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
BMC Anesthesiol. 2023 Aug 18;23(1):279. doi: 10.1186/s12871-023-02230-w.
The present study aimed to assess variables associated to ICU-mortality among patients admitted to surgical intensive care unit in Ethiopia.
A Hospital-based retrospective follow-up study was conducted on all patients who were admitted to the surgical intensive care unit. Data were extracted from patients' charts with a pretested data extraction tool, entered into Epi-data 4.6.0, and analyzed with STATA- 14. Bivariate and multivariate Cox proportional hazards regression models were fitted.
Of the total study participants (388), 148 (38.1%) patients admitted to the surgical intensive care unit died during the follow-up period with a median survival time of 11 days. Potassium level < 3.5 mmol/L (adjusted hazard ratio ( AHR): 3.46, 95% CI (1.83 6.55), potassium level > 5.0 mmol/L (AHR:2.41, 95% CI (1.29-4.51), hypoxia (AHR:1.66, 95% CI (1.10-2.48), Glasgow Coma Scale (GCS) score < 9 (AHR: 4.06, 95% CI (1.51-10.89), mechanical ventilation (AHR:12, 95%CI (3-45), absence of thromboprophylaxis (AHR:10.8,95% CI (6.04-19.29), absence of enteral feeding (AHR:3.56, 95% CI (2.20-5.78) were variables associated with ICU-mortality among patients admitted to surgical intensive care unit.
The overall ICU-mortality of patients admitted to our surgical intensive care unit was higher compared to patients admitted to similar intensive care unit in developed countries. The variables associated to ICU-mortality among patients admitted to surgical intensive care unit were abnormal serum potassium level, lower GCS score, mechanical support, hypoxia, absence of thromboprophylaxis, and enteral feeding.
本研究旨在评估埃塞俄比亚外科重症监护病房(SICU)患者 ICU 死亡率的相关变量。
对所有入住 SICU 的患者进行基于医院的回顾性随访研究。使用经过预测试的数据提取工具从患者病历中提取数据,将其输入 Epi-data 4.6.0,并使用 STATA-14 进行分析。拟合了双变量和多变量 Cox 比例风险回归模型。
在总共 388 名研究参与者中,有 148 名(38.1%)患者在随访期间入住 SICU 期间死亡,中位生存时间为 11 天。血清钾水平 <3.5mmol/L(调整后的危险比(AHR):3.46,95%置信区间(CI)(1.83 6.55)),血清钾水平 >5.0mmol/L(AHR:2.41,95%CI(1.29-4.51)),缺氧(AHR:1.66,95%CI(1.10-2.48)),格拉斯哥昏迷评分(GCS)<9(AHR:4.06,95%CI(1.51-10.89)),机械通气(AHR:12,95%CI(3-45)),无血栓预防(AHR:10.8,95%CI(6.04-19.29)),无肠内喂养(AHR:3.56,95%CI(2.20-5.78))是与入住 SICU 的患者 ICU 死亡率相关的变量。
与发达国家类似重症监护病房(ICU)的患者相比,入住我们外科 ICU 的患者的总体 ICU 死亡率较高。与入住外科 ICU 的患者 ICU 死亡率相关的变量包括血清钾水平异常、GCS 评分较低、机械支持、缺氧、无血栓预防和肠内喂养。