Theotonio Dos Santos Lucas Ferreira, Marques Fidalgo Thiago, Cordeiro Mattos Antônio José, Albuquerque Ribeiro Geylene, Rizzo Luiz Vicente, Andrade Rodrigues Fonseca Henrique
Academic Research Organization, Instituto Israelita de Ensino e Pesquisa - Hospital Israelita Albert Einstein, São Paulo, Brazil.
Department of Psychiatry, Escola Paulista de Medicina - Universidade Federal de São Paulo, São Paulo, Brazil.
Hum Vaccin Immunother. 2025 Dec;21(1):2517488. doi: 10.1080/21645515.2025.2517488. Epub 2025 Jul 3.
HPV is a common sexually transmitted infection (STI), often affecting young women. Although most infections are asymptomatic, high-risk types of HPV can cause multiple types of cancer, especially cervical cancer. Brazil's 2014 national HPV vaccination campaign, targeting girls aged 11 to 13, improved awareness and vaccine coverage. However, challenges such as vaccine hesitancy and the ongoing need for educational interventions persist, highlighting the need for additional studies to better understand factors influencing vaccine uptake among adolescents. This study analyzed data from the 2019 PeNSE survey, focusing on HPV vaccination information in the dataset. It also examined factors like socioeconomic conditions, family context, and access to education and healthcare. The study found that access to information through cellphones increased HPV vaccine uptake, particularly among females. Indigenous adolescents had higher vaccination odds compared to White adolescents, likely due to campaigns that aimed at vulnerable individuals. Overall, any degree of maternal schooling, compared to no formal education, was related to higher odds of being vaccinated. Sexual health education, particularly on pregnancy prevention and STIs, also boosted vaccine uptake, likely due to overlapping content that includes HPV-related information. The student population presents an opportunity for improving HPV vaccination coverage through parental and school education, healthcare information, and targeted optimization strategies for both genders. Future studies should be designed to leverage these opportunities to achieve the WHO goal of 90% vaccination coverage among girls by age 15 by 2030.
人乳头瘤病毒（HPV）是一种常见的性传播感染（STI），常影响年轻女性。尽管大多数感染没有症状，但高危型HPV可导致多种类型的癌症，尤其是宫颈癌。巴西2014年针对11至13岁女孩的全国HPV疫苗接种运动提高了认知度和疫苗接种覆盖率。然而，疫苗犹豫等挑战以及持续需要开展教育干预措施的情况依然存在，这凸显了开展更多研究以更好地了解影响青少年疫苗接种率的因素的必要性。本研究分析了2019年全国学生健康调查（PeNSE）的数据，重点关注数据集中的HPV疫苗接种信息。研究还考察了社会经济状况、家庭环境以及获得教育和医疗保健的机会等因素。研究发现，通过手机获取信息可提高HPV疫苗接种率，尤其是在女性当中。与白人青少年相比，土著青少年接种疫苗的几率更高，这可能是由于针对弱势群体开展的运动。总体而言，与未接受正规教育相比，母亲接受任何程度的学校教育都与更高的接种几率相关。性健康教育，特别是关于预防怀孕和性传播感染的教育，也提高了疫苗接种率，这可能是因为其中包含了与HPV相关信息等重叠内容。学生群体为通过家长和学校教育、医疗保健信息以及针对两性的有针对性的优化策略来提高HPV疫苗接种覆盖率提供了契机。未来的研究应旨在利用这些机会，以实现世界卫生组织提出的到2030年15岁女孩的疫苗接种覆盖率达到90%的目标。
