Hoxha Din, Bayro Jablonski Nikolai E, Chatterjee Arjun, Abdallah Jennifer, Cartabuke Richard
Department of Internal Medicine Cleveland Clinic.
Division of Gastroenterology. Hepatology and Nutrition Cleveland Clinic.
J Brown Hosp Med. 2025 Jul 1;4(3):137218. doi: 10.56305/001c.137218. eCollection 2025.
Erythromelalgia is a rare condition characterized by severe paroxysmal pain in the extremities and erythema that leads to significant morbidity and incapacity. We report on the case of a female with a history of erythromelalgia, presenting with worsening bilateral leg pain and purple discoloration of her feet following a surgical procedure. After ruling out secondary causes, a diagnosis of atypical erythromelalgia flare was established. A multimodal pain management strategy was instituted, and the patient improved upon follow-up. The clinical presentation of erythromelalgia presents diagnostic and therapeutic challenges, and atypical presentations highlight our poor understanding of the disease.
红斑性肢痛症是一种罕见病症，其特征为四肢严重的阵发性疼痛和红斑，会导致显著的发病率和功能丧失。我们报告一例有红斑性肢痛症病史的女性病例，该患者在一次手术后出现双侧腿部疼痛加重及足部紫绀。排除继发原因后，确诊为非典型红斑性肢痛症发作。制定了多模式疼痛管理策略，患者在随访时病情有所改善。红斑性肢痛症的临床表现带来了诊断和治疗方面的挑战，而非典型表现凸显了我们对该疾病的了解不足。
