Chen Song, Lu Siwei, Sun Yuelin, Wang Wenlei, Chen Yingfu, Li Jing, Liu Chengjun
Department of Critical Care Medicine, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Chongqing, China.
Front Pediatr. 2025 Jun 19;13:1604298. doi: 10.3389/fped.2025.1604298. eCollection 2025.
A lung abscess is a thick-walled cavity containing purulent material that results from pulmonary infection. It is an uncommon condition that can occur at any age. Bronchopleural fistula (BPF) is a severe complication with a poor prognosis that may arise with the progression of the condition or as a result of treatment.
We describe a case of lung abscess complicated by a BPF and septic shock in a 7-year-old girl. A chest tube was inserted and venoarterial extracorporeal membrane oxygenation (ECMO) was emergently used. To selectively block the BPF, an endobronchial blocker was placed in the right intermediate bronchus under bronchoscopic guidance. This approach allowed the BPF to heal, enabled the recruitment of the other lung, and obstructed the purulent fluid. The patient recovered and was discharged after 70 days of treatment.
This case demonstrates that combined endobronchial blocker and ECMO can be an effective approach for patients with lung abscesses and BPFs (especially those aged < 8 years) when the adjustment of conventional therapy is unsuccessful.
肺脓肿是一种由肺部感染导致的、含有脓性物质的厚壁空洞。它是一种不常见的病症,可发生于任何年龄。支气管胸膜瘘(BPF)是一种严重并发症,预后较差,可能随着病情进展或治疗而出现。
我们描述了一名7岁女孩发生肺脓肿合并支气管胸膜瘘及感染性休克的病例。插入了胸管,并紧急使用了静脉-动脉体外膜肺氧合(ECMO)。为了选择性封堵支气管胸膜瘘,在支气管镜引导下将支气管内封堵器置于右中间支气管。这种方法使支气管胸膜瘘愈合,使另一侧肺复张,并阻塞了脓性液体。患者经70天治疗后康复出院。
本病例表明,当常规治疗调整失败时,支气管内封堵器与ECMO联合使用对于肺脓肿合并支气管胸膜瘘患者(尤其是年龄<8岁者)可能是一种有效的治疗方法。