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一名儿童患有双侧大量恶性卵巢生殖细胞肿瘤并伴有癌转移。

Voluminous bilateral malignant ovarian germ cell tumors with carcinomatosis in a child.

作者信息

Boujida Nadia, Elaitari Khadija, Jabour Soukayna, El Kababri Maria, Hessissein Laila, Lamalmi Najat, Allali Nazik, Chat Latifa, Haddad Siham El

机构信息

Radiology Department Children's University Hospital Rabat.

Oncology Department Children's University Hospital Rabat.

出版信息

Radiol Case Rep. 2025 Jun 21;20(9):4497-4503. doi: 10.1016/j.radcr.2025.05.096. eCollection 2025 Sep.

Abstract

Ovarian germ cell tumors (OGCTs) are rare malignancies, predominantly affecting adolescents and young women. We present the case of a 14-year-old girl with a 1-month history of progressive abdominal distension, vomiting, and diffuse abdominal pain. Imaging revealed large bilateral pelvic masses with significant peritoneal effusion and peritoneal carcinomatosis. The diagnosis of a malignant germ cell tumor was confirmed through histological analysis. The patient was treated with 6 cycles of chemotherapy, showing favorable progression. This case highlights the diagnostic challenges and therapeutic considerations in managing OGCTs, emphasizing the importance of early detection and fertility-preserving surgical strategies.

摘要

卵巢生殖细胞肿瘤(OGCTs)是罕见的恶性肿瘤,主要影响青少年和年轻女性。我们报告一例14岁女孩,有1个月进行性腹胀、呕吐和弥漫性腹痛病史。影像学检查发现双侧盆腔有巨大肿块,伴有大量腹腔积液和腹膜转移瘤。通过组织学分析确诊为恶性生殖细胞肿瘤。该患者接受了6个周期的化疗,病情进展良好。本病例突出了OGCTs管理中的诊断挑战和治疗考量,强调了早期检测和保留生育功能手术策略的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a14/12226073/2a9e1ac00fd2/gr1.jpg

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