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Eur Rev Med Pharmacol Sci. 2025 Jun;29(6):287-288. doi: 10.26355/eurrev_202506_37270.
The Publisher, in agreement with the Editor-in-Chief, is issuing this Expression of Concern to inform readers that a formal investigation is currently underway regarding a set of published articles. Despite multiple attempts to contact the corresponding authors, we have not received any response to date. Further editorial actions, such as retraction or correction, will be taken as appropriate in due course. The articles under investigation fall into the following categories. These studies report extended follow-up periods, yet were published prior to the actual conclusion of the declared follow-up. This discrepancy raises serious concerns about the validity of the timeline and outcome reporting: Liao Y, Cheng S, Xiang J, Luo C. lncRNA CCHE1 increased proliferation, metastasis and invasion of non-small lung cancer cells and predicted poor survival in non-small lung cancer patients. Eur Rev Med Pharmacol Sci. 2018 Mar;22(6):1686-1692. doi: 10.26355/eurrev_201803_14581. PMID: 29630113. Yao N, Sun JQ, Yu L, Ma L, Guo BQ. LINC00968 accelerates the progression of epithelial ovarian cancer via mediating the cell cycle progression. Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4642-4649. doi: 10.26355/eurrev_201906_18043. PMID: 31210289. Hao XZ, Yang K. LncRNA MAGI2-AS3 suppresses the proliferation and invasion of non-small cell lung carcinoma through miRNA-23a-3p/PTEN axis. Eur Rev Med Pharmacol Sci. 2019 Sep;23(17):7399-7407. doi: 10.26355/eurrev_201909_18848. PMID: 31539127. Jiang J, Wu RH, Zhou HL, Li ZM, Kou D, Deng Z, Dong M, Chen LH. TGIF2 promotes cervical cancer metastasis by negatively regulating FCMR. Eur Rev Med Pharmacol Sci. 2020 Jun;24(11):5953-5962. doi: 10.26355/eurrev_202006_21488. PMID: 32572908. These articles have been questioned as they appear to reuse identical or similar graphical elements and images from a shared library across multiple unrelated studies: Xu CF, Liu P, Tan J, Hu DF. Long noncoding RNA LINC00052 suppressed the proliferation, migration and invasion of glioma cells by upregulating KLF6. Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4822-4827. doi: 10.26355/eurrev_201906_18068. PMID: 31210314. Zheng FX, Wang XQ, Zheng WX, Zhao J. Long noncoding RNA HOXA-AS2 promotes cell migration and invasion via upregulating IGF-2 in non-small cell lung cancer as an oncogene. Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4793-4799. doi: 10.26355/eurrev_201906_18064. PMID: 31210310. Liao J, Xie N. Long noncoding RNA DSCAM-AS1 functions as an oncogene in non-small cell lung cancer by targeting BCL11A. Eur Rev Med Pharmacol Sci. 2019 Feb;23(3):1087-1092. doi: 10.26355/eurrev_201902_16998. PMID: 30779076. Lu J, Xu FQ, Guo JJ, Lin PL, Meng Z, Hu LG, Li J, Li D, Lu XH, An Y. Long noncoding RNA GAS5 attenuates cardiac fibroblast proliferation in atrial fibrillation via repressing ALK5. Eur Rev Med Pharmacol Sci. 2019 Sep;23(17):7605-7610. doi: 10.26355/eurrev_201909_18883. PMID: 31539152. Shi JQ, Wang B, Cao XQ, Wang YX, Cheng X, Jia CL, Wen T, Luo BJ, Liu ZD. Circular RNA_LARP4 inhibits the progression of non-small-cell lung cancer by regulating the expression of SMAD7. Eur Rev Med Pharmacol Sci. 2020 Feb;24(4):1863-1869. doi: 10.26355/eurrev_202002_20364. PMID: 32141555. Cui K, Zhang H, Wang GZ. MiR-483 suppresses cell proliferation and promotes cell apoptosis by targeting SOX3 in breast cancer. Eur Rev Med Pharmacol Sci. 2019 Mar;23(5):2069-2074. doi: 10.26355/eurrev_201903_17248. PMID: 30915751. Ren L, Zhai H, Wang XL, Li JZ, Xia YH. Hsa_circ_0011946 promotes the migration and invasion of hepatocellular carcinoma by inducing EMT process. Eur Rev Med Pharmacol Sci. 2020 Feb;24(3):1108-1115. doi: 10.26355/eurrev_202002_20161. PMID: 32096173. Chen RX, Liu HL, Yang LL, Kang FH, Xin LP, Huang LR, Guo QF, Wang YL. Circular RNA circRNA_0000285 promotes cervical cancer development by regulating FUS. Eur Rev Med Pharmacol Sci. 2019 Oct;23(20):8771-8778. doi: 10.26355/eurrev_201910_19271. PMID: 31696463. Liu T, Wang W, Xu YC, Li ZW, Zhou J. Long noncoding RNA NEAT1 functions as an oncogene in human laryngocarcinoma by targeting miR-29a-3p. Eur Rev Med Pharmacol Sci. 2019 Jul;23(14):6234-6241. doi: 10.26355/eurrev_201907_18442. PMID: 31364125. Liu WG, Xu Q. Long non-coding RNA XIST promotes hepatocellular carcinoma progression by sponging miR-200b-3p. Eur Rev Med Pharmacol Sci. 2019 Nov;23(22):9857-9862. doi: 10.26355/eurrev_201911_19549. PMID: 31799653. Weng XD, Yan T, Liu CL. Circular RNA_LARP4 inhibits cell migration and invasion of prostate cancer by targeting FOXO3A. Eur Rev Med Pharmacol Sci. 2020 May;24(10):5303-5309. doi: 10.26355/eurrev_202005_21312. PMID: 32495863. He XY, Pan XM, Jin MM, Yang YL, Yang ZQ, Yan D, Ma JX. Long non-coding RNA AK027294 promotes tumor growth by upregulating PCNA in gastric cancer. Eur Rev Med Pharmacol Sci. 2019 Jul;23(13):5762-5769. doi: 10.26355/eurrev_201907_18314. PMID: 31298327. Wang YH, Huo BL, Li C, Ma G, Cao W. Knockdown of long noncoding RNA SNHG7 inhibits the proliferation and promotes apoptosis of thyroid cancer cells by downregulating BDNF. Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4815-4821. doi: 10.26355/eurrev_201906_18067. PMID: 31210313. Yang ZT, An F, Hu JD, Zhao WH. Long noncoding RNA AFAP1-AS1 accelerates the proliferation and metastasis of prostate cancer via inhibiting RBM5 expression. Eur Rev Med Pharmacol Sci. 2019 Apr;23(8):3284-3290. doi: 10.26355/eurrev_201904_17690. PMID: 31081081. Ma LY, Xie XW, Ma L, Pang JL, Xiong XM, Zheng HD, Shen XL, Wen ZG, Wang HY. Downregulated long non-coding RNA TRPM2-AS inhibits cisplatin resistance of non-small cell lung cancer cells via activation of p53- p66shc pathway. Eur Rev Med Pharmacol Sci. 2017 Jun;21(11):2626-2634. PMID: 28678322. The following publications have been questioned for showing recurrent structural patterns and visual content (e.g., Kaplan-Meier plots, correlation graphs, etc.) across a large set of articles: Li XF, Aierken AL, Shen L. IPO5 promotes malignant progression of esophageal cancer through activating MMP7. Eur Rev Med Pharmacol Sci. 2020 Apr;24(8):4246-4254. doi: 10.26355/eurrev_202004_21004. PMID: 32373960. Gao WY, Yang G, Wang J, He JM, Wang P. CSN6 promotes malignant progression of oral squamous cell carcinoma by down-regulating TIMP-2. Eur Rev Med Pharmacol Sci. 2020 May;24(10):5419-5428. doi: 10.26355/eurrev_202005_21326. PMID: 32495877. Shi XY, Lin JJ, Ge XJ, Shi Y. LncRNA WTAPP1 promotes proliferation of laryngeal carcinoma cells through regulating microRNA-592. Eur Rev Med Pharmacol Sci. 2020 Sep;24(18):9532-9540. doi: 10.26355/eurrev_202009_23038. PMID: 33015795. Hou YS, Li X. Circ_0005273 induces the aggravation of pancreatic cancer by targeting KLF12. Eur Rev Med Pharmacol Sci. 2020 Nov;24(22):11578-11586. doi: 10.26355/eurrev_202011_23799. PMID: 33275224. Yang Y, Mao FF, Guo L, Guo WX. TRIM56 suppresses the malignant development of hepatocellular carcinoma via targeting RBM24 and inactivating the Wnt signaling. Eur Rev Med Pharmacol Sci. 2021 Jan;25(2):722-730. doi: 10.26355/eurrev_202101_24633. PMID: 33577026. The Publisher apologizes for any inconvenience this may cause.
出版商与主编达成一致，发布此关注声明，以告知读者目前正在对一组已发表的文章进行正式调查。尽管多次尝试联系通讯作者，但截至目前我们尚未收到任何回复。后续将在适当的时候采取进一步的编辑措施，如撤稿或勘误。正在调查的文章分为以下几类。这些研究报告了延长的随访期，但在声明的随访实际结束之前就已发表。这种差异引发了对时间线和结果报告有效性的严重担忧：廖Y、程S、向J、罗C。lncRNA CCHE1促进非小细胞肺癌细胞的增殖、转移和侵袭，并预测非小细胞肺癌患者的不良生存。《欧洲医学与药理学评论》。2018年3月；22(6):1686 - 1692。doi: 10.26355/eurrev_201803_14581。PMID: 29630113。姚N、孙JQ、余L、马L、郭BQ。LINC00968通过介导细胞周期进程加速上皮性卵巢癌的进展。《欧洲医学与药理学评论》。2019年6月；23(11):4642 - 4649。doi: 10.26355/eurrev_201906_18043。PMID: 31210289。郝XZ、杨K。lncRNA MAGI2 - AS3通过miRNA - 23a - 3p/PTEN轴抑制非小细胞肺癌的增殖和侵袭。《欧洲医学与药理学评论》。2019年9月；23(17):7399 - 7407。doi: 10.26355/eurrev_201909_18848。PMID: 31539127。姜J、吴RH、周HL、李ZM、寇D、邓Z、董M、陈LH。TGIF2通过负调控FCMR促进宫颈癌转移。《欧洲医学与药理学评论》。2020年6月；24(11):5953 - 5962。doi: 10.26355/eurrev_202006_21488。PMID: 32572908。这些文章受到质疑，因为它们似乎在多个不相关的研究中重复使用了来自共享图库的相同或相似的图形元素和图像：徐CF、刘P、谭J、胡DF。长链非编码RNA LINC00052通过上调KLF6抑制胶质瘤细胞的增殖、迁移和侵袭。《欧洲医学与药理学评论》。2019年6月；23(11):4822 - 4827。doi: 10.26355/eurrev_201906_18068。PMID: 31210314。郑FX、王XQ、郑WX、赵J。长链非编码RNA HOXA - AS2作为癌基因通过上调IGF - 2促进非小细胞肺癌细胞的迁移和侵袭。《欧洲医学与药理学评论》。2019年6月；23(11):4793 - 4799。doi: 10.26355/eurrev_201906_18064。PMID: 31210310。廖J、谢N。长链非编码RNA DSCAM - AS1通过靶向BCL11A在非小细胞肺癌中发挥癌基因作用。《欧洲医学与药理学评论》。2019年2月；23(3):1087 - 1092。doi: 10.26355/eurrev_201902_16998。PMID: 30779076。陆J、徐FQ、郭JJ、林PL、孟Z、胡LG、李J、李D、陆XH、安Y。长链非编码RNA GAS5通过抑制ALK5减轻心房颤动中心肌成纤维细胞的增殖。《欧洲医学与药理学评论》。2019年9月；23(17):7605 - 7610。doi: 10.26355/eurrev_201909_18883。PMID: 31539152。石JQ、王B、曹XQ、王YX、程X、贾CL、温T、罗BJ、刘ZD。环状RNA_LARP4通过调节SMAD7的表达抑制非小细胞肺癌的进展。《欧洲医学与药理学评论》。2020年2月；24(4):1863 - 1869。doi: 10.26355/eurrev_202002_20364。PMID: 32141555。崔K、张H、王GZ。MiR - 483通过靶向SOX3抑制乳腺癌细胞增殖并促进细胞凋亡。《欧洲医学与药理学评论》。2019年3月；23(5):2069 - 2074。doi: 10.26355/eurrev_201903_17248。PMID: 30915751。任L、翟H、王XL、李JZ、夏YH。Hsa_circ_0011946通过诱导EMT过程促进肝细胞癌的迁移和侵袭。《欧洲医学与药理学评论》。2020年2月；24(3):1108 - 1115。doi: 10.26355/eurrev_202002_20161。PMID: 32096173。陈RX、刘HL、杨LL、康FH、辛LP、黄LR、郭QF、王YL。环状RNA circRNA_0000285通过调节FUS促进宫颈癌发展。《欧洲医学与药理学评论》。2019年10月；23(20):8771 - 8778。doi: 10.26355/eurrev_201910_19271。PMID: 31696463。刘T、王W、徐YC、李ZW、周J。长链非编码RNA NEAT1通过靶向miR - 29a - 3p在人喉癌中发挥癌基因作用。《欧洲医学与药理学评论》。2019年7月；23(14):6234 - 6241。doi: 10.26355/eurrev_201907_18442。PMID: 31364125。刘WG、徐Q。长链非编码RNA XIST通过海绵吸附miR - 200b - 3p促进肝细胞癌进展。《欧洲医学与药理学评论》。2019年11月；23(22):9857 - 9862。doi: 10.26355/eurrev_201911_19549。PMID: 31799653。翁XD、严T、刘CL。环状RNA_LARP4通过靶向FOXO3A抑制前列腺癌细胞的迁移和侵袭。《欧洲医学与药理学评论》。2020年5月；24(10):5303 - 5309。doi: 10.26355/eurrev_202005_21312。PMID: 32495863。何XY、潘XM、金MM、杨YL、杨ZQ、严D、马JX。长链非编码RNA AK027294通过上调PCNA促进胃癌肿瘤生长。《欧洲医学与药理学评论》。2019年7月；23(13):5762 - 5769。doi: 10.26355/eurrev_201907_18314。PMID: 31298327。王YH、霍BL、李C、马G、曹W。敲低长链非编码RNA SNHG7通过下调BDNF抑制甲状腺癌细胞的增殖并促进其凋亡。《欧洲医学与药理学评论》。2019年6月；23(11):4815 - 4821。doi: 10.26355/eurrev_201906_18067。PMID: 31210313。杨ZT、安F、胡JD、赵WH。长链非编码RNA AFAP1 - AS1通过抑制RBM5表达加速前列腺癌的增殖和转移。《欧洲医学与药理学评论》。2019年4月；23(8):3284 - 3290。doi: 10.26355/eurrev_201904_17690。PMID: 31081081。马LY、谢XW、马L、庞JL、熊XM、郑HD、沈XL、温ZG、王HY。下调的长链非编码RNA TRPM2 - AS通过激活p53 - p66shc途径抑制非小细胞肺癌细胞的顺铂耐药性。《欧洲医学与药理学评论》。2017年6月；21(11):2626 - 2634。PMID: 28678322。以下出版物因在大量文章中呈现重复的结构模式和视觉内容（如Kaplan - Meier图、相关图等）而受到质疑：李XF、艾尔肯·AL、沈L。IPO5通过激活MMP7促进食管癌的恶性进展。《欧洲医学与药理学评论》。2020年4月；24(8):4246 - 4254。doi: 10.26355/eurrev_202004_21004。PMID: 32373960。高WY、杨G、王J、何JM、王P。CSN6通过下调TIMP - 2促进口腔鳞状细胞癌的恶性进展。《欧洲医学与药理学评论》。2020年5月；24(10):5419 - 5428。doi: 10.26355/eurrev_202005_21326。PMID: 32495877。石XY、林JJ、葛XJ、石Y。lncRNA WTAPP1通过调节microRNA - 592促进喉癌细胞增殖。《欧洲医学与药理学评论》。2020年9月；24(18):9532 - 9540。doi: 10.26355/eurrev_202009_23038。PMID: 33015795。侯YS、李X。Circ_0005273通过靶向KLF12诱导胰腺癌病情加重。《欧洲医学与药理学评论》。2020年11月；24(22):11578 - 11586。doi: 10.26355/eurrev_202011_23799。PMID: 33275224。杨Y、毛FF、郭L、郭WX。TRIM56通过靶向RBM24并使Wnt信号失活抑制肝细胞癌的恶性发展。《欧洲医学与药理学评论》。2021年1月；25(2):722 - 730。doi: 10.26355/eurrev_202101_24633。PMID: 33577026。出版商对由此可能造成的任何不便表示歉意。
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