Wang Tong, He Yanni, Yi Wenhong, Xie Huiyu, Wang Dan, Zeng Jie, Liang Jinying, Chen Yufan, Mo Qiuyan, Zhou Meijun, Li Sushu, Huang Feifei, Liu Shaoming, Ma Liya, Liu Xueling, Liu Hongmei
Department of Ultrasound, Institute of Ultrasound in Musculoskeletal Sports Medicine, Guangdong Engineering Technology Research Center of Emergency Medicine, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangdong, Guangzhou, 510317, People's Republic of China.
The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510317, People's Republic of China.
BMC Musculoskelet Disord. 2025 Jul 4;26(1):637. doi: 10.1186/s12891-025-08864-w.
This study aimed to explore conventional ultrasound sonography and shear wave elastography (SWE) changes in the supraspinatus tendon in type 2 diabetes patients (T2DM) without shoulder pain. The factors influencing supraspinatus tendon thickness and shear wave velocity (SWV), which are measured by SWE, were also explored.
This multicenter study recruited nonshoulder pain individuals, including healthy and diabetic patients from March 2021 to October 2022. Propensity score matching was used to overcome selection bias. The thickness and SWV of the bilateral supraspinatus tendons were measured, and their influencing factors were evaluated via regression analysis. The sonography and blood flow signals were observed and compared via χ2 tests.
A total of 107 T2DM patients and 270 healthy people were enrolled (mean age, 42 years ± 14, 162 men). Although 59.8% of T2DM patients without shoulder pain, they were likely to have degenerative ultrasonic image and a lower SWV (-0.529 [-0.827, -0.232] vs. 1; p = 0.001) than healthy people, but no difference was detected for uneven thickening of the tendon (p = 0.055) or blood flow signals (p = 0.060). Furthermore, subjects > 50 years old, with a BMI ≥ 25.0 and who were of Chinese Zhuang population had thicker supraspinatus tendons than did the controls. Chinese Han population and regular upper limb exercise subjects had greater tendon SWV than did controls.
SWE is a repeatable and early tool for assessing supraspinatus tendon degeneration in asymptomatic patients with T2DM. Active control of the condition of diabetes patients and regular upper limb exercise might help delay the degeneration of supraspinatus tendons.
本研究旨在探讨无肩部疼痛的2型糖尿病患者（T2DM）冈上肌腱的传统超声检查及剪切波弹性成像（SWE）变化。同时还探讨了影响通过SWE测量的冈上肌腱厚度和剪切波速度（SWV）的因素。
本多中心研究于2021年3月至2022年10月招募了无肩部疼痛的个体，包括健康人和糖尿病患者。采用倾向得分匹配法以克服选择偏倚。测量双侧冈上肌腱的厚度和SWV，并通过回归分析评估其影响因素。通过χ2检验观察并比较超声检查结果和血流信号。
共纳入107例T2DM患者和270例健康人（平均年龄42岁±14岁，男性162例）。尽管59.8%的T2DM患者无肩部疼痛，但他们的超声图像可能出现退变，且SWV低于健康人（-0.529 [-0.827, -0.232] vs. 1；p = 0.001），不过在肌腱不均匀增厚（p = 0.055）或血流信号方面（p = 0.060）未发现差异。此外，年龄>50岁、BMI≥25.0以及中国壮族人群的冈上肌腱比对照组更厚。中国汉族人群和经常进行上肢锻炼的受试者的肌腱SWV高于对照组。
SWE是评估无症状T2DM患者冈上肌腱退变的一种可重复且早期的工具。积极控制糖尿病患者病情并定期进行上肢锻炼可能有助于延缓冈上肌腱退变。
