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马拉维抗逆转录病毒治疗启动及早期留存策略中利益相关方的优先事项:一项比较国际和国家视角的定性研究

Stakeholder priorities for ART initiation and early retention strategies in Malawi: a qualitative study comparing international and national perspectives.

作者信息

Hariprasad Santhi, Phiri Khumbo, Thorp Marguerite, Holland Katherine, Nyirenda Rose, Gupta Sundeep, Phiri Sam, Sabin Lora L, Dovel Kathryn

机构信息

Department of Global Health, School of Public Health, Boston University, Boston, 02118, MA, USA.

Partners in Hope, Lilongwe, Malawi.

出版信息

BMC Public Health. 2025 Jul 5;25(1):2388. doi: 10.1186/s12889-025-23484-8.

Abstract

INTRODUCTION

New or returning antiretroviral therapy (ART) clients are largely ineligible for differentiated service delivery (DSD) models. These clients are at increased risk of treatment interruption and may benefit from flexible care models, but stakeholder buy-in may limit progress on interventions for this population. We qualitatively explored stakeholder perceptions and decision-making criteria for scaling DSD models for new or returning ART clients in Malawi.

METHODS

We conducted in-depth interviews with internationally-based stakeholders (from foundations, multilateral organizations, and non-governmental organizations (NGOs)) and Malawi-based stakeholders (from the Malawi Ministry of Health and local implementing partners). Interviews included two think-aloud scenarios in which participants rated and described their perceptions of (1) the relative priority of five criteria (cost, effectiveness, acceptability, feasibility, and equity) in determining which interventions to implement for new or returning ART clients and (2) the relative priority of seven potential interventions (monetary incentives, non-monetary incentives, community-based care, ongoing peer/mentor support and counseling, eHealth, facility-based interventions, and multi-month dispensing) for the same population. Interviews were completed in English via video conference and were audio-recorded. Transcriptions were coded using ATLAS.ti version 9. We examined the data using thematic content analysis and explored differences between international and national stakeholders.

RESULTS

We interviewed twenty-two stakeholders between October 2021-March 2022. Thirteen were based internationally and nine were based in Malawi. Both groups prioritized client acceptability, but diverged on other criteria: international stakeholders prioritized effectiveness and Malawi-based stakeholders prioritized cost, feasibility, and sustainability. Both stakeholder groups were most interested in facility-based DSD models such as multi-month dispensing and extended facility hours. Nearly all stakeholders described person-centered care as a critical focus to incorporate into all DSD models.

CONCLUSIONS

National and international stakeholders support DSD models for new or returning ART clients. Client acceptability and sustainability should be prioritized to address the concerns of nationally-based stakeholders. Future studies should explore reasons for differences in national and international stakeholders’ priorities and how to ensure that local perspectives are incorporated into funding and programmatic decisions.

摘要

引言

新的或重新开始接受抗逆转录病毒治疗(ART)的患者基本上不符合差异化服务提供(DSD)模式的条件。这些患者治疗中断的风险增加,可能会从灵活的护理模式中受益,但利益相关者的支持可能会限制针对这一人群的干预措施的进展。我们对马拉维新的或重新开始接受ART治疗的患者扩大DSD模式的利益相关者认知和决策标准进行了定性探索。

方法

我们对国际利益相关者(来自基金会、多边组织和非政府组织(NGO))和马拉维利益相关者(来自马拉维卫生部和当地实施伙伴)进行了深入访谈。访谈包括两个出声思考场景,参与者对以下内容进行评分并描述他们的看法:(1)在确定对新的或重新开始接受ART治疗的患者实施哪些干预措施时,五个标准(成本、有效性、可接受性、可行性和公平性)的相对优先级;(2)针对同一人群的七种潜在干预措施(金钱激励、非金钱激励、社区护理、持续的同伴/导师支持与咨询、电子健康、基于设施的干预措施和多月配药)的相对优先级。访谈通过视频会议用英语完成,并进行了录音。转录内容使用ATLAS.ti 9版本进行编码。我们使用主题内容分析法对数据进行了分析,并探讨了国际和国内利益相关者之间的差异。

结果

我们在2021年10月至2022年3月期间采访了22名利益相关者。其中13名来自国际,9名来自马拉维。两组都将患者可接受性列为优先事项,但在其他标准上存在分歧:国际利益相关者将有效性列为优先事项,而马拉维利益相关者将成本、可行性和可持续性列为优先事项。两组利益相关者都对基于设施的DSD模式最感兴趣,如多月配药和延长设施服务时间。几乎所有利益相关者都将以人为本的护理描述为纳入所有DSD模式的关键重点。

结论

国家和国际利益相关者支持针对新的或重新开始接受ART治疗的患者的DSD模式。应优先考虑患者可接受性和可持续性,以解决国内利益相关者的担忧。未来的研究应探讨国家和国际利益相关者优先事项差异的原因,以及如何确保将当地观点纳入资金和项目决策中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fdd/12228217/a86117682e9c/12889_2025_23484_Fig1_HTML.jpg

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