Gulec Busra, Gul Pinar, Erdemci Burak
Kastamonu Oral and Dental Health Center, Kastamonu, Turkey.
Department of Restorative Dentistry, Faculty of Dentistry, Atatürk University, Erzurum, Turkey.
BMC Oral Health. 2025 Jul 5;25(1):1103. doi: 10.1186/s12903-025-06219-4.
In patients receiving head and neck radiotherapy, ensuring and maintaining oral hygiene is very important to minimize oral complications. In order to evaluate the clinical success of restorative materials used in the treatment of dental caries, it is important to know the toxic potential of the type and amount of ions released from the restorative material as well as their mechanical properties. The aim of this study is to determine the monomer released from the materials after radiotherapy is applied to 13 different dental restorative materials based dimethacrylate resin.
13 different restorative materials were used. 20 specimens were prepared from each material and specimens were randomly divided into two equal groups: experimental and control groups (n = 10). A total of 60 Gy of radiation was applied to the experimental group. During the 6-week radiotherapy procedure, the samples were kept in 75% ethanol-water solution. The monomer analysis of the collected specimens was performed using the LC-MS/MS system. The analysis of the data obtained was performed using Mann-Whitney U and Kruskal Wallis tests (α = 0.05).
It was determined that the amount of monomer released was mostly less in the radiotherapy group than in the control group. Significant differences were found among restorative materials in terms of monomer release (p < 0.05). In terms of monomer release amounts, the highest release was from composite resin group materials, while the least was from resin ceramic materials.
Within the limits of this study, it was found that the amounts of monomer released from the investigated materials were mostly lower after radiotherapy. In addition, the amounts of monomer release were higher in the composite group materials, while the release was lower in the resin ceramics.
在接受头颈部放疗的患者中,确保并维持口腔卫生对于将口腔并发症降至最低非常重要。为了评估用于治疗龋齿的修复材料的临床成功率,了解修复材料释放的离子类型和数量的潜在毒性及其机械性能很重要。本研究的目的是确定对13种基于二甲基丙烯酸酯树脂的不同牙科修复材料进行放疗后从材料中释放的单体。
使用了13种不同的修复材料。每种材料制备20个标本,标本随机分为两组:实验组和对照组(n = 10)。对实验组施加总共60 Gy的辐射。在为期6周的放疗过程中,将样品保存在75%乙醇-水溶液中。使用LC-MS/MS系统对收集的标本进行单体分析。使用Mann-Whitney U检验和Kruskal Wallis检验(α = 0.05)对获得的数据进行分析。
确定放疗组释放的单体量大多比对照组少。在修复材料之间发现单体释放方面存在显著差异(p < 0.05)。就单体释放量而言,复合树脂组材料释放量最高,而树脂陶瓷材料释放量最少。
在本研究的范围内,发现放疗后所研究材料释放的单体量大多较低。此外,复合组材料的单体释放量较高,而树脂陶瓷的释放量较低。