Department of Restorative Dentistry, Faculty of Dentistry, Bolu Abant Izzet Baysal University, Bolu, Turkey.
Department of Restorative Dentistry, Faculty of Dentistry, Atatürk University, TR-25240, Erzurum, Turkey.
Clin Oral Investig. 2022 Jun;26(6):4647-4662. doi: 10.1007/s00784-022-04446-5. Epub 2022 Mar 17.
The aim of this study is to determine the type and amount of monomer released over time after bleaching was applied to dental restorative materials containing dimethacrylate resin.
Thirteen different restorative materials containing dimethacrylate resin were used in this study. Twenty samples were prepared from each material and the samples were randomly divided into 4 subgroups, namely, office bleaching, home bleaching, and separate control group for each of the bleaching methods. After bleaching, the samples were stored in 75% ethanol solution for 1, 14, and 28 days. Analysis of the samples collected to determine the type and amount of residual monomer released from the materials was performed using a liquid chromatography-tandem mass/mass spectrometer (LC-MS/MS). Data were analyzed using Friedman and Kruskal-Wallis tests. Statistical significance level was taken as p < 0.05.
In terms of bleaching groups, mostly no significant difference was found between the groups in each time period in restorative materials (p > 0.05). In terms of time periods, it was determined that the amount of release of all monomers was decreased over time. In terms of restorative materials, the highest monomer release was detected in composite resin groups and the least monomer release was detected in CAD/CAM blocks.
Although monomers were released from all materials, bleaching did not affect the amount of released monomer. Amounts of released monomers were generally below toxic limits.
Within the limits of this study, bleaching does not significantly affect monomer release in restorative materials containing dimethacrylate resin.
本研究旨在确定在含有二甲基丙烯酸酯树脂的牙科修复材料上进行漂白后，随着时间的推移释放的单体类型和数量。
本研究使用了 13 种含有二甲基丙烯酸酯树脂的不同修复材料。每种材料制备 20 个样本，将样本随机分为 4 组，即诊室漂白组、家庭漂白组和每种漂白方法的单独对照组。漂白后，将样本储存在 75%乙醇溶液中 1、14 和 28 天。使用液相色谱-串联质谱/质谱联用仪（LC-MS/MS）分析收集的样本，以确定从材料中释放的残留单体的类型和数量。使用 Friedman 和 Kruskal-Wallis 检验对数据进行分析。统计显著性水平设为 p<0.05。
在漂白组方面，在每个时间段，各组之间在修复材料中大多没有发现显著差异（p>0.05）。在时间段方面，随着时间的推移，所有单体的释放量逐渐减少。在修复材料方面，复合材料组中单体释放量最高，CAD/CAM 块中单体释放量最低。
尽管所有材料都释放了单体，但漂白并未影响释放单体的数量。释放单体的量通常低于毒性限值。
在本研究范围内，漂白不会显著影响含有二甲基丙烯酸酯树脂的修复材料中单体的释放。
