The practical approach to the evaluation of suspected environmental exposures: chemical intolerance.

The purpose of this article is to encourage allergists to expand their interest in environmental intolerance to include chemicals found in everyday exposure. By incorporating controlled challenge procedures into outpatient practice capabilities, the practicing allergist can expand both clinical interest and practice potential. By merging scientific principles of toxicology and psychology with the traditional investigative skills of the well-trained clinical allergist, we believe that discipline of allergy/immunology can realize a rather remarkable new dimension.