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中国的高血压控制:从临床试验到实际应用的转化——初步结果

Hypertension Control in China: Translation from Clinical Trial to Real-World Application - Preliminary Outcomes.

作者信息

Sun Guozhe, Peng Hao, Liu Songyue, Wang Chang, Tan Xiangyu, Fu Jia, Dong Wenlan, Liu Fang, Guo Xiaofan, Qiao Lixia, Ouyang Nanxiang, Miao Wei, Geng Danxi, Yin Yangzhi, Xie Ziyi, Zhang Pengyu, Zhang Caiyu, He Chenhua, Wu Jing, Sun Yingxian

机构信息

Department of Cardiology, the First Hospital of China Medical University, Shenyang City, Liaoning Province, China.

Department of Epidemiology, School of Public Health Suzhou Medical College of Soochow University, Suzhou City, Jiangsu Province, China.

出版信息

China CDC Wkly. 2025 May 16;7(20):685-689. doi: 10.46234/ccdcw2025.113.

Abstract

To evaluate the adaptability of the China Rural Hypertension Control Project (CRHCP) - a multifaceted village doctor-led intervention for blood pressure control in rural China - for widespread implementation in extension projects. This project comprises two phases: a pilot project and an extension project. It builds upon our CRHCP model, implementing a multi-level comprehensive hypertension management strategy targeting the general population across rural areas and township communities in China, aligning with national policies and local initiatives. In the pilot project, 5,088 hypertensive patients were enrolled. At baseline, 1,227 subjects (25.7%) met the 140/90 mmHg target for blood pressure control. After 13 months of intervention, the blood pressure control rate (<140/90 mmHg) reached 72.5%. In the extension project, 244,046 hypertensive patients were identified through screening of 1,002,845 residents in Changtu, Wujiang, and Tongguan. Average blood pressure decreased from 146.8/88.4 mmHg to 140.4/82.6 mmHg, and the proportion of patients with controlled blood pressure increased significantly from 20.8% to 44.0%. The translation of the CRHCP model into a public health program has demonstrated potential for enhancing hypertension control in selected regions of China. While these initial results are encouraging, further research and long-term evaluation are needed to confirm their effectiveness and adaptability. If proven successful, this model may offer a replicable framework for improving public health outcomes in other low- and middle-income countries and regions.

摘要

评估中国农村高血压控制项目(CRHCP)——一项由乡村医生主导的多方面血压控制干预措施——在推广项目中广泛实施的适应性。该项目包括两个阶段:试点项目和推广项目。它基于我们的CRHCP模式,实施针对中国农村地区和乡镇社区普通人群的多层次综合高血压管理策略,与国家政策和地方举措保持一致。在试点项目中,招募了5088名高血压患者。基线时,1227名受试者(25.7%)达到了140/90 mmHg的血压控制目标。经过13个月的干预,血压控制率(<140/90 mmHg)达到72.5%。在推广项目中,通过对昌图、吴江和潼关1002845名居民进行筛查,确定了244046名高血压患者。平均血压从146.8/88.4 mmHg降至140.4/82.6 mmHg,血压得到控制的患者比例从20.8%显著增加到44.0%。将CRHCP模式转化为公共卫生项目已显示出在中国选定地区加强高血压控制的潜力。虽然这些初步结果令人鼓舞,但仍需要进一步研究和长期评估来确认其有效性和适应性。如果证明成功,该模式可能为改善其他低收入和中等收入国家及地区的公共卫生成果提供一个可复制的框架。

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