Zaman Maham, Fida Tooba, Haris Hafiz Muhammad, Naveed Zarmeen, Haider Shaheer, Khan Tauqeer
Quaid-e-Azam Medical College, Bahawalpur, Pakistan.
King Edward Medical University, Lahore, Pakistan.
Acta Parasitol. 2025 Jul 7;70(4):150. doi: 10.1007/s11686-025-01091-2.
Naegleria fowleri, a thermophilic, free-living amoeba, is the causative agent of Primary Amebic Meningoencephalitis (PAM), a rare but highly fatal infection.
This case report highlights a 31-year-old physical trainer from Ichhra, Lahore, who presented with symptoms of headache, fever, and altered behavior, ultimately diagnosed with Primary Amebic Meningoencephalitis (PAM) based on cerebrospinal fluid (CSF) wet mount microscopy findings, with domestic water suspected as the probable source due to the absence of recreational water exposure.
The case underscores the urgent need for early diagnosis and intervention to combat the rising mortality rates associated with this deadly infection. The impact of factors such as rising temperatures and compromised water systems on the spread of Naegleria fowleri in Pakistan is discussed, emphasizing the importance of public health measures to prevent further cases.
福氏耐格里阿米巴是一种嗜热的自由生活阿米巴，是原发性阿米巴脑膜脑炎（PAM）的病原体，这是一种罕见但致死率很高的感染。
本病例报告重点介绍了一名来自拉合尔伊赫拉的31岁体育教练，他出现头痛、发热和行为改变的症状，最终根据脑脊液（CSF）湿片显微镜检查结果被诊断为原发性阿米巴脑膜脑炎（PAM），由于没有接触娱乐用水，怀疑家庭用水是可能的感染源。
该病例强调了早期诊断和干预以应对与这种致命感染相关的死亡率上升的迫切需要。讨论了气温上升和水系统受损等因素对巴基斯坦福氏耐格里阿米巴传播的影响，强调了公共卫生措施对预防更多病例的重要性。
