Wagner Till, Nienhuijs Marloes, Berge Stefaan, Ulrich Dietmar
Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
Maxillofac Plast Reconstr Surg. 2025 Jul 7;47(1):16. doi: 10.1186/s40902-025-00470-z.
The clinical outcome of unilateral cleft lip closure depends on both the incision pattern and vertical scar retraction as well as complete lip muscle closure. Existing techniques focus on the lengthening of the cleft side with reducing visible scarring in addition to correct muscle adaptation but are still struggling with scar contraction. We aimed to optimize clinical results by developing a new incision design integrating benefits of established techniques with our own considerations.
A study-using 10 adult cadavers-compared two vertical incision lines: the Millard advancement-rotation flap and our Z-back-cut cheiloplasty which reassembles a Z-plasty at the nostril by combining with a back cut at the lower columella rim. A skin distraction model assessed the impact of tension on lengthening. Our technique demonstrated increased vertical height compared to Millard's method. Based on these findings, we applied our approach in clinical settings.
The Millard flap showed significantly less elongation (up to 35%) between the lateral cupid's bow and the columella base than our method. This suggests that the Z-plasty principle is beneficial in unilateral cleft lip closure. Clinical outcomes confirmed its applicability in both partial and complete clefts.
Applying our findings in pediatric patients yielded at least equivalent results to the Millard II technique, even in cases with postoperative wound infections and increased contraction risk.
Our research supports integrating Z-plasty principles into unilateral cleft lip repair. We plan to use this technique in future surgeries where indicated.
单侧唇裂修复的临床效果取决于切口模式、垂直瘢痕挛缩以及唇部肌肉的完全闭合。现有技术除了注重正确的肌肉适配外,还着重于延长患侧并减少可见瘢痕,但仍难以解决瘢痕挛缩问题。我们旨在通过开发一种新的切口设计来优化临床效果,该设计融合了现有技术的优点并融入了我们自己的考量。
一项使用10具成年尸体的研究比较了两条垂直切口线:米勒德推进旋转皮瓣和我们的Z形后切唇成形术,后者通过在鼻小柱下缘进行后切与鼻孔处的Z成形术相结合。一个皮肤牵张模型评估了张力对延长的影响。与米勒德法相比,我们的技术显示垂直高度增加。基于这些发现,我们将该方法应用于临床。
与我们的方法相比,米勒德皮瓣在外侧丘比特弓与鼻小柱基部之间的伸长明显更少(高达35%)。这表明Z成形术原则在单侧唇裂修复中是有益的。临床结果证实了其在部分和完全性唇裂中的适用性。
将我们的发现应用于儿科患者,即使在术后伤口感染和挛缩风险增加的病例中,也至少能取得与米勒德II技术相当的效果。
我们的研究支持将Z成形术原则纳入单侧唇裂修复。我们计划在未来有指征的手术中使用该技术。