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德国达姆施塔特化脓性汗腺炎的患病率:对全球化脓性汗腺炎地图集的贡献。

Prevalence of Hidradenitis Suppurativa in Darmstadt, Germany: A Contribution to the Global Hidradenitis Suppurativa Atlas.

作者信息

Steinmetz Marten I, Bouazzi Dorra, Kovács Maximilian, Medianfar Cecilia E, Christensen Robin, Jemec Gregor B E, Podda Maurizio

机构信息

Department of Dermatology, Medical Center Klinikum Darmstadt, Teaching Hospital Goethe-University Frankfurt, Darmstadt, Germany.

Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.

出版信息

Dermatology. 2025 Jul 7:1-6. doi: 10.1159/000539285.

Abstract

INTRODUCTION

The knowledge of the epidemiology of hidradenitis suppurativa (HS) in Germany is currently insufficient. This study aimed to determine the prevalence of HS in Darmstadt, Germany, and contribute to the Global Hidradenitis Suppurativa Atlas (GHiSA).

METHODS

This monocentric, cross-sectional study was conducted at the Klinikum Darmstadt, Germany, from January to February 2024. Data from 519 healthy accompanying adults were included after obtaining oral and written consent. A validated screening questionnaire, used as an index test before clinical examination, was performed on screening-positive and randomly selected screening-negative participants as a reference test.

RESULTS

The prevalence of HS in Darmstadt, Germany, was 1.16% (6/519; confidence interval: 0.95: 0.53%-2.50%). The HS group had a median age of 37.5 years and a median BMI of 32.5. No predominance of sex or smoking status could be found in the HS group and there were no statistical differences between the groups in sex, age, or smoking status. However, the median BMI was significantly higher in the HS group.

CONCLUSION

The study found the prevalence of HS in Darmstadt, Germany, to be 1.16%, which is significantly higher than previously reported rates in Germany. This study found an association between BMI and HS. However, it did not observe the previously reported association between HS and sex or smoking status. The questionnaire used is a valid screening tool for HS in the assessment of the general population.

摘要

引言

目前在德国,对化脓性汗腺炎(HS)流行病学的了解尚不充分。本研究旨在确定德国达姆施塔特市HS的患病率,并为全球化脓性汗腺炎地图集(GHiSA)提供数据。

方法

本单中心横断面研究于2024年1月至2月在德国达姆施塔特市立医院进行。在获得口头和书面同意后,纳入了519名健康陪同成年人的数据。在临床检查前,使用经过验证的筛查问卷作为指标测试,对筛查呈阳性的参与者以及随机选择的筛查呈阴性的参与者进行参考测试。

结果

德国达姆施塔特市HS的患病率为1.16%(6/519;置信区间:0.95:0.53%-2.50%)。HS组的中位年龄为37.5岁,中位体重指数为32.5。HS组在性别或吸烟状况方面没有明显优势,两组在性别、年龄或吸烟状况方面没有统计学差异。然而,HS组的中位体重指数显著更高。

结论

该研究发现德国达姆施塔特市HS的患病率为1.16%,这显著高于德国此前报告的患病率。该研究发现体重指数与HS之间存在关联。然而,未观察到此前报告的HS与性别或吸烟状况之间的关联。所使用的问卷是评估普通人群中HS的有效筛查工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1567/12233969/b3eadc91b934/drm-2025-0000-0000-539285_F01.jpg

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