荷移植性黑色素瘤仓鼠血清补体依赖细胞毒作用的研究
Study on the complement-dependent cytotoxic effect of the sera of hamsters bearing transplanted melanoma.
作者信息
Kozłowska K, Zurawska-Czupa B, Kostulak A
出版信息
Arch Immunol Ther Exp (Warsz). 1985;33(3):435-42.
PMID:4062508
Abstract
Complement-dependent cytotoxic effect of the sera of hamsters bearing transplanted melanomas: melanotic and amelanotic, was examined in relation to isolated melanocytes of these melanomas. A specific, cytotoxic effect, ranging 34-47% of the sera of hamsters with both types of melanomas in relation to the cells of these tumors was found. No relationship between the biological properties of melanoma and cytotoxic activity of serum was noted.
摘要
携带移植性黑色素瘤（包括黑素性和无黑素性）的仓鼠血清的补体依赖性细胞毒性作用，针对这些黑色素瘤的分离黑素细胞进行了检测。发现两种类型黑色素瘤的仓鼠血清对这些肿瘤细胞具有特异性细胞毒性作用，范围在34%至47%之间。未观察到黑色素瘤的生物学特性与血清细胞毒性活性之间的关系。
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