Rekhacheva I P, Katinas G S, Sapronenkova I N
Arkh Anat Gistol Embriol. 1985 Sep;89(9):49-55.
In 105 male rats of Wistar strain distal parts of one of the thoracic extremities are amputated with keeping intact the places where the brachial muscle is fixed. This does not restrict the volume of the brachium movements but essentially decreases their dynamic component (power loading). For 45 days dynamics of succinate-dehydrogenase (SDG) activity is being revealed in muscle fibers (MF) of functionally different muscles: m. brachialis, m. serratus ventralis and m. triceps brachii (the medial head). Average tendency of the process, changes in the distribution margins, asymmetry and kurtosis are taken into account. Under hypodynamia reconstruction of the MF has a wavy character with a gradually longer period of fluctuations. In all the muscles appear MF with a greater than in the control SDG activity. In the medial head of the m. triceps brachii the fibers with the lowest SDG activity disappear. The amount of MF with the lowest activity decreases, while those with the higher--increases, the process being more pronounced in the m. triceps brachii. The amount of MF with middle activity of the enzyme remains nearly unchanged. MF with different initial enzymatic activity do not change simultaneously. The degree of the changes in the fibers and the power leading are connected with each other, the fibers with the low initial SDG activity including into the reaction at a sharper decrease of the latter. The changes in quantitative ratio of MF with different SDG activity are not the same in every muscle studied.
在105只雄性Wistar大鼠中,切除一侧胸肢的远端部分,同时保持肱肌固定部位完好。这并不限制臂部运动的幅度,但实质上降低了其动态成分(功率负荷)。在45天的时间里,对功能不同的肌肉:肱肌、腹侧锯肌和肱三头肌(内侧头)的肌纤维(MF)中琥珀酸脱氢酶(SDG)活性的动态变化进行了研究。考虑了该过程的平均趋势、分布范围的变化、不对称性和峰度。在动力不足的情况下,MF的重建具有波浪状特征,波动周期逐渐变长。在所有肌肉中,出现了SDG活性高于对照组的MF。在肱三头肌内侧头,SDG活性最低的纤维消失。活性最低的MF数量减少,而活性较高的MF数量增加,这一过程在肱三头肌中更为明显。酶活性中等的MF数量几乎保持不变。具有不同初始酶活性的MF并非同时发生变化。纤维变化程度与功率变化程度相互关联,初始SDG活性低的纤维在后者急剧下降时更易参与反应。在每块研究的肌肉中,具有不同SDG活性的MF数量比例变化并不相同。