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The Arming of Natural Killer Cells With Fc-Engineered Monoclonal Antibodies Confers Specificity Against Tumor B Cells.

作者信息

Constantinides Michaël, Coënon Loïs, Falvo Paolo, Multrier Caroline, Lombardi Davide, Bertolini Francesco, Martineau Pierre, Robert Bruno, Cartron Guillaume, Villalba Martin

机构信息

IRMB, University of Montpellier INSERM CHU Montpellier Montpellier France.

Department of Clinical Hematology CHU Montpellier Montpellier France.

出版信息

MedComm (2020). 2025 Jul 4;6(7):e70242. doi: 10.1002/mco2.70242. eCollection 2025 Jul.

DOI:10.1002/mco2.70242
PMID:40626322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12231191/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5053/12231191/0f1c23da2aae/MCO2-6-e70242-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5053/12231191/0f1c23da2aae/MCO2-6-e70242-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5053/12231191/0f1c23da2aae/MCO2-6-e70242-g001.jpg

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本文引用的文献

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Natural Killer cells at the frontline in the fight against cancer.自然杀伤细胞在抗击癌症的第一线。
Cell Death Dis. 2024 Aug 23;15(8):614. doi: 10.1038/s41419-024-06976-0.
2
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J Immunother Cancer. 2024 Jul 18;12(7):e009070. doi: 10.1136/jitc-2024-009070.
3
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19 B cell tumors: a phase 1/2 trial.同种异体 CD19 特异性 CAR-NK 细胞治疗 CD19 B 细胞肿瘤的安全性、有效性和反应决定因素:一项 1/2 期试验。
Nat Med. 2024 Mar;30(3):772-784. doi: 10.1038/s41591-023-02785-8. Epub 2024 Jan 18.
4
Advancements in CAR-NK therapy: lessons to be learned from CAR-T therapy.嵌合抗原受体自然杀伤(CAR-NK)细胞疗法的进展:从嵌合抗原受体 T(CAR-T)细胞疗法中吸取的经验教训。
Front Immunol. 2023 May 2;14:1166038. doi: 10.3389/fimmu.2023.1166038. eCollection 2023.
5
Direct Cell Death Induced by CD20 Monoclonal Antibodies on B Cell Lymphoma Cells Revealed by New Protocols of Analysis.新分析方案揭示CD20单克隆抗体对B细胞淋巴瘤细胞的直接细胞死亡作用
Cancers (Basel). 2023 Feb 9;15(4):1109. doi: 10.3390/cancers15041109.
6
Dual targeting of the DNA damage response pathway and BCL-2 in diffuse large B-cell lymphoma.双重靶向弥漫性大 B 细胞淋巴瘤的 DNA 损伤反应通路和 BCL-2。
Leukemia. 2022 Jan;36(1):197-209. doi: 10.1038/s41375-021-01347-6. Epub 2021 Jul 24.
7
Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors.利用高效抗体依赖的细胞毒性对多种肿瘤进行同种异体 NK 细胞扩增。
Theranostics. 2018 Jun 14;8(14):3856-3869. doi: 10.7150/thno.25149. eCollection 2018.
8
The cellular immune system in myelomagenesis: NK cells and T cells in the development of MM and their uses in immunotherapies.骨髓瘤发生中的细胞免疫系统:自然杀伤细胞和T细胞在多发性骨髓瘤发展中的作用及其在免疫治疗中的应用。
Blood Cancer J. 2015 Jul 3;5(7):e321. doi: 10.1038/bcj.2015.49.
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