灾变论和焦虑是全膝关节置换术后慢性疼痛的危险因素:一项前瞻性队列研究。
Catastrophism and anxiety are risk factors of chronic pain after total knee arthroplasty : a prospective cohort study.
作者信息
Croppi Clara, Delaigue Fanny, Guinebertière Violaine, Devriese Flore, Bizot Pascal, Descamps Jules, Nizard Rémy, Bouché Pierre-Alban
机构信息
Service de chirurgie orthopédique et traumatologique, Hôpital Lariboisière, AP-HP, Paris, France.
Université Médecine Paris-Cité, Paris, France.
出版信息
Bone Jt Open. 2025 Jul 4;6(7):755-763. doi: 10.1302/2633-1462.67.BJO-2024-0270.R1.
AIMS
After a total knee arthroplasty (TKA), up to 40% of patients suffer from chronic pain. Few studies have focused specifically on psychosocial factors as predictors of chronic pain after TKA. Our study aims to identify psychosocial risk factors of chronic pain after TKA and to identify an optimal threshold for significant scores in the multivariate analysis, using a receiver operating characteristic (ROC) curve.
METHODS
This was a single-centre prospective study conducted from September 2022 to September 2023, involving 204 patients. The mean age was 70 years (SD 8.59), the mean BMI was 30.49 kg/m (SD 5.29), and 70.60% of patients were female (144/204). A form was administered before surgery to collect: Hospital Anxiety and Depression Scale (HADS), anxiety scale State-Trait Anxiety Inventory (STAI)-Y, Amsterdam Preoperative Anxiety and Information Scale (APAIS), Pain Catastrophizing Scale (PCS), and visual analogue scale (VAS). Univariate and multivariate logistic regression was used to determine the risk factors associated with chronic pain. To determine a threshold in the psychological scores associated with chronic pain, ROC curves were performed.
RESULTS
A total of 36 patients (17.60%) met the definition of chronic pain, defined as VAS ≥ 4/10 at six months postoperatively. In the multivariate analysis, to be an employee or worker ( = 1.10, 95% CI 0.20 to 2.10, p = 0.018), anxiety STAI-YB ( = 0.03, 95% CI 0.01 to 0.06, p = 0.013), and catastrophism PCS ( = 0.04, 95% CI 0.02 to 0.06, p < 0.001) were associated with chronic pain after TKA. Using ROC analysis, we identified a threshold value of 44.5 for anxiety STAI-YB (sensitivity 57.58%, specificity 74.51%) and of 21.5 for catastrophism PCS (sensitivity 56,25 %, specificity 71.90%) of developing chronic pain after TKA.
CONCLUSION
This study shows that the psychosocial profile of patients can be linked to the occurrence of chronic pain, and underlines the importance of a multidimensional approach to patient assessment and management.
目的
全膝关节置换术(TKA)后,高达40%的患者会遭受慢性疼痛。很少有研究专门关注心理社会因素作为TKA后慢性疼痛的预测指标。我们的研究旨在确定TKA后慢性疼痛的心理社会风险因素,并使用受试者工作特征(ROC)曲线确定多变量分析中显著评分的最佳阈值。
方法
这是一项于2022年9月至2023年9月进行的单中心前瞻性研究,涉及204名患者。平均年龄为70岁(标准差8.59),平均体重指数为30.49kg/m(标准差5.29),70.60%的患者为女性(144/204)。术前发放一份表格以收集:医院焦虑抑郁量表(HADS)、焦虑量表状态-特质焦虑问卷(STAI)-Y、阿姆斯特丹术前焦虑与信息量表(APAIS)、疼痛灾难化量表(PCS)和视觉模拟量表(VAS)。采用单变量和多变量逻辑回归来确定与慢性疼痛相关的风险因素。为了确定与慢性疼痛相关的心理评分阈值,绘制了ROC曲线。
结果
共有36名患者(17.60%)符合慢性疼痛的定义,定义为术后6个月VAS≥4/10。在多变量分析中,身为雇员或工人(比值比=1.10,95%置信区间0.20至2.10,p=0.018)、焦虑STAI-YB(比值比=0.03,95%置信区间0.01至0.06,p=...
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