Li Yan, Yin Na, Li Chao, Yang Shi-Wei
Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China.
Medicine (Baltimore). 2025 Jul 4;104(27):e43215. doi: 10.1097/MD.0000000000043215.
This study analyzed Global Burden of Disease (GBD) 2019 data to assess cardiovascular disease (CVD) burden in women worldwide. Using annual incident cases, deaths, age-standardized incidence (ASIR), and mortality rates (ASMR) from 1990-2019, trends were evaluated via percentage changes and estimated annual percentage change (EAPC). Globally, incident CVD cases in women rose by 73.86% (15.90 to 27.64 million), while deaths increased by 47.45% (6.06 to 8.94 million). Despite this, ASIR (EAPC: -0.57%) and ASMR (EAPC: -1.63%) declined. Regional disparities emerged in ischemic heart disease (IHD): ASIR increased in low/middle socio-demographic index (SDI) regions (EAPC: +0.04% and + 0.08%) but decreased in high-middle/high SDI regions (EAPC: -1.09% and -2.24%). Findings highlight persistent IHD incidence growth in lower-resource settings despite global improvements in age-standardized rates.
本研究分析了《2019年全球疾病负担》（GBD 2019）数据，以评估全球女性心血管疾病（CVD）负担。利用1990年至2019年的年度发病病例、死亡人数、年龄标准化发病率（ASIR）和死亡率（ASMR），通过百分比变化和估计年度百分比变化（EAPC）评估趋势。在全球范围内，女性心血管疾病发病病例增加了73.86%（从1590万例增至2764万例），而死亡人数增加了47.45%（从606万例增至894万例）。尽管如此，年龄标准化发病率（EAPC：-0.57%）和年龄标准化死亡率（EAPC：-1.63%）仍有所下降。缺血性心脏病（IHD）出现了地区差异：在社会人口统计学指数（SDI）较低/中等的地区，年龄标准化发病率上升（EAPC：+0.04%和+0.08%），而在社会人口统计学指数较高/中等的地区则下降（EAPC：-1.09%和-2.24%）。研究结果突出表明，尽管全球年龄标准化发病率有所改善，但在资源匮乏地区，缺血性心脏病的发病率仍持续增长。
