Li Rui, Wang Meng, Li Shaoxin, Liao Lin
Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, Shandong Institute of Nephrology, Jinan, China.
First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Front Oncol. 2025 Jun 24;15:1539586. doi: 10.3389/fonc.2025.1539586. eCollection 2025.
Acquired pure red cell aplasia (PRCA) has attracted more and more attention in hematology. PRCA usually caused by infection, autoimmune diseases, thymic carcinoma, or drugs, has not been reported by radioactive iodine. Here we report a case of PRCA after radioactive iodine therapies (two times, 100 mCi and 130 mCi each) in a patient with papillary thyroid carcinoma and follow up for two years. she was treatment with cyclosporine (100mg twice per day), stanozolol (2mg three times per day) and diammonium glycyrrhizinate (150mg three times per day), returned to the normal range in 2024.
获得性纯红细胞再生障碍性贫血（PRCA）在血液学领域越来越受到关注。PRCA通常由感染、自身免疫性疾病、胸腺癌或药物引起，放射性碘导致的PRCA尚未见报道。在此，我们报告1例乳头状甲状腺癌患者在接受两次放射性碘治疗（每次分别为100mCi和130mCi）后发生PRCA，并随访两年的病例。她接受环孢素（每日2次，每次100mg）、司坦唑醇（每日3次，每次2mg）和甘草酸二铵（每日3次，每次150mg）治疗，于2024年恢复至正常范围。
