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本文引用的文献

1
Type-2-low severe asthma endotypes for new treatments: the new asthma frontier.新型治疗方法的2型低重度哮喘内型:哮喘新前沿。
Curr Opin Allergy Clin Immunol. 2023 Jun 1;23(3):199-204. doi: 10.1097/ACI.0000000000000899. Epub 2023 Apr 12.
2
Identification and treatment of T2-low asthma in the era of biologics.生物制剂时代T2低型哮喘的识别与治疗
ERJ Open Res. 2021 Jun 7;7(2). doi: 10.1183/23120541.00309-2020. eCollection 2021 Apr.
3
Neutrophilic asthma: misconception or misnomer?嗜中性粒细胞性哮喘:误解还是用词不当?
Lancet Respir Med. 2021 May;9(5):441-443. doi: 10.1016/S2213-2600(21)00023-0. Epub 2021 Feb 9.
4
Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program.重度哮喘研究计划中混合痰液粒细胞对肺功能的纵向影响。
Am J Respir Crit Care Med. 2021 Apr 1;203(7):882-892. doi: 10.1164/rccm.202009-3713OC.
5
Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping.老年哮喘的特征是痰中性粒细胞增多、下气道口径变化和空气滞留。
Respir Res. 2021 Jan 13;22(1):15. doi: 10.1186/s12931-021-01619-w.
6
Asthma and fixed airflow obstruction: Long-term trajectories suggest distinct endotypes.哮喘与固定性气流受限:长期轨迹提示不同的内型。
Clin Exp Allergy. 2021 Jan;51(1):39-48. doi: 10.1111/cea.13714. Epub 2020 Aug 14.
7
Elevated serum IgE, oral corticosteroid dependence and IL-17/22 expression in highly neutrophilic asthma.高嗜中性粒细胞性哮喘患者血清 IgE 升高、口服皮质类固醇依赖和 IL-17/22 表达。
Eur Respir J. 2019 Nov 7;54(5). doi: 10.1183/13993003.00068-2019. Print 2019 Nov.
8
Dysregulation of sputum columnar epithelial cells and products in distinct asthma phenotypes.不同表型哮喘中外分泌柱状上皮细胞及其产物的失调。
Clin Exp Allergy. 2019 Nov;49(11):1418-1428. doi: 10.1111/cea.13452. Epub 2019 Aug 6.
9
Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis.聚类分析显示,痰中性粒细胞计数与更严重的哮喘表型相关。
J Allergy Clin Immunol. 2014 Jun;133(6):1557-63.e5. doi: 10.1016/j.jaci.2013.10.011. Epub 2013 Dec 9.
10
Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects.生物标志物替代物不能准确预测哮喘患者痰液中嗜酸性粒细胞和中性粒细胞的百分比。
J Allergy Clin Immunol. 2013 Jul;132(1):72-80. doi: 10.1016/j.jaci.2013.03.044. Epub 2013 May 21.

探索哮喘中的中性粒细胞模式:“中度”和“高度”嗜中性粒细胞患者是同一类人群吗?

Exploring the neutrophilic pattern in asthma: are "intermediate" and "high" neutrophilic patients the same population?

作者信息

Visca Dina, Ardesi Francesco, Zappa Martina, Pignatti Patrizia, Centis Rosella, Migliori Giovanni Battista, Fassio Federico, Baiardi Paola, Vanetti Marco, Ricciardolo Fabio Luigi Massimo, Spanevello Antonio

机构信息

Department of Medicine and Surgery, University of Insubria, Varese, Italy.

Department of Medicine and Cardiopulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy.

出版信息

ERJ Open Res. 2025 Jul 7;11(4). doi: 10.1183/23120541.01109-2024. eCollection 2025 Jul.

DOI:10.1183/23120541.01109-2024
PMID:40630385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12230749/
Abstract

https://bit.ly/4hmP0Z3.

摘要

https://bit.ly/4hmP0Z3. (此为链接,无法准确翻译其内容,保留原文链接形式)