Michalopoulos George C, Bikeyeva Viktoriya, Paolella Giovanni, Adams Joseph, Labchuk Andrii, Chaus Adib
Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, USA.
Cardiology, Advocate Lutheran General Hospital, Park Ridge, USA.
Cureus. 2025 Jul 7;17(7):e87468. doi: 10.7759/cureus.87468. eCollection 2025 Jul.
Non-occlusive mesenteric ischemia (NOMI) is a rare complication after transcatheter aortic valve replacement (TAVR), with a poorly understood pathogenesis. We present the case of a 79-year-old female with a history of surgically repaired abdominal aortic aneurysm (AAA) and stable thoracic aortic aneurysm (TAA) who developed NOMI after TAVR, resulting in extensive bowel necrosis and patient mortality. Our case highlights the special attention that must be paid to patients with a history of endovascular interventions prior to TAVR due to the risk of postprocedural NOMI. We propose that NOMI after TAVR occurs from the reduction in cardiac output due to rapid pacing during valve deployment, resulting in worsening splanchnic hypoperfusion in patients with existing mesenteric vascular disease.
非闭塞性肠系膜缺血(NOMI)是经导管主动脉瓣置换术(TAVR)后一种罕见的并发症,其发病机制尚不清楚。我们报告了一例79岁女性患者,有腹主动脉瘤(AAA)手术修复史和稳定的胸主动脉瘤(TAA),在TAVR后发生NOMI,导致广泛肠坏死和患者死亡。我们的病例强调,由于TAVR术后发生NOMI的风险,对于有血管内介入治疗史的患者,在TAVR前必须给予特别关注。我们认为,TAVR后发生NOMI是由于瓣膜植入过程中快速起搏导致心输出量减少,从而使已有肠系膜血管疾病的患者内脏灌注不足加重。