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阴道癌:2025年最新进展

Cancer of the vagina: 2025 update.

作者信息

Adams Tracey S, Maluleke Jackie Choekoe, Cuello Mauricio A

机构信息

Department of Obstetrics and Gynaecology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

University of Cape Town Gynecological Cancer Research Center (UCT GCRC), Cape Town, South Africa.

出版信息

Int J Gynaecol Obstet. 2025 Sep;171 Suppl 1:48-59. doi: 10.1002/ijgo.70325. Epub 2025 Jul 9.

DOI:10.1002/ijgo.70325
PMID:40631450
Abstract

Primary vaginal cancer is a rare gynecologic malignancy, with most vaginal cancers representing metastases from other primary sites. Staging and treatment protocols are often extrapolated from those used in cervical cancer. In contemporary medicine, the roles of the pathologist and radiologist are increasingly vital in supporting diagnosis and staging. Given the rarity of this malignancy, referral to centers of excellence is recommended for further assessment and treatment.

摘要

原发性阴道癌是一种罕见的妇科恶性肿瘤,大多数阴道癌为其他原发部位的转移瘤。分期和治疗方案通常借鉴宫颈癌的相关方案。在当代医学中,病理学家和放射科医生在辅助诊断和分期方面的作用愈发重要。鉴于这种恶性肿瘤较为罕见,建议转诊至专业中心进行进一步评估和治疗。

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引用本文的文献

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本文引用的文献

1
ESTRO/ESGO/SIOPe Guidelines for the management of patients with vaginal cancer.ESTRO/ESGO/SIOP 阴道癌管理患者指南。
Int J Gynecol Cancer. 2023 Aug 7;33(8):1185-1202. doi: 10.1136/ijgc-2023-004695.
2
Role of MRI in the Assessment of Cervical Cancer.磁共振成像在宫颈癌评估中的作用。
Semin Ultrasound CT MR. 2023 Jun;44(3):228-237. doi: 10.1053/j.sult.2023.03.010. Epub 2023 Mar 28.
3
The European Society of Gynaecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Disease (ISSVD), the European College for the Study of Vulval Disease (ECSVD), and the European Federation for Colposcopy (EFC) Consensus Statement on the Management of Vaginal Intraepithelial Neoplasia.
欧洲妇科肿瘤学会(ESGO)、国际外阴阴道疾病研究学会(ISSVD)、欧洲外阴疾病研究学院(ECSVD)和欧洲阴道镜检查学会(EFC)关于阴道上皮内瘤变管理的共识声明。
J Low Genit Tract Dis. 2023 Apr 1;27(2):131-145. doi: 10.1097/LGT.0000000000000732.
4
Sarcoma Botryoides: Optimal Therapeutic Management and Prognosis of an Unfavorable Malignant Neoplasm of Female Children.葡萄状肉瘤:女童恶性肿瘤的最佳治疗管理与预后
Diagnostics (Basel). 2023 Mar 1;13(5):924. doi: 10.3390/diagnostics13050924.
5
Data Set for the Reporting of Carcinomas of the Vagina: Recommendations From the International Collaboration on Cancer Reporting (ICCR).阴道癌报告数据集:国际癌症报告合作组织(ICCR)的建议。
Int J Gynecol Pathol. 2022 Nov 1;41(Suppl 1):S23-S33. doi: 10.1097/PGP.0000000000000883. Epub 2022 May 20.
6
Updates in the treatment of vaginal cancer.阴道癌治疗的新进展。
Int J Gynecol Cancer. 2022 Mar;32(3):344-351. doi: 10.1136/ijgc-2021-002517.
7
Vaginal cancer: Why should we care? Anatomy, staging and in-depth imaging-based review of vaginal malignancies focusing on MRI and PET/CT.阴道癌:我们为何要关注?阴道恶性肿瘤的解剖学、分期及基于影像学的深入评估——着重于 MRI 和 PET/CT
Clin Imaging. 2022 Apr;84:65-78. doi: 10.1016/j.clinimag.2022.01.009. Epub 2022 Feb 3.
8
Screening History in Vaginal Precancer and Cancer: A Retrospective Study of 2131 Cases in China.阴道癌前病变和癌症的筛查史:中国2131例病例的回顾性研究
Cancer Manag Res. 2021 Nov 26;13:8855-8863. doi: 10.2147/CMAR.S335701. eCollection 2021.
9
Risk factors analysis of persistence, progression and recurrence in vaginal intraepithelial neoplasia.阴道上皮内瘤变持续、进展和复发的危险因素分析。
Gynecol Oncol. 2021 Sep;162(3):584-589. doi: 10.1016/j.ygyno.2021.06.027. Epub 2021 Jul 3.
10
Real-World Effectiveness of Human Papillomavirus Vaccination Against Vulvovaginal High-Grade Precancerous Lesions and Cancers.人乳头瘤病毒疫苗接种对阴道外阴高级别癌前病变和癌症的真实世界有效性。
J Natl Cancer Inst. 2021 Jul 1;113(7):869-874. doi: 10.1093/jnci/djaa209.