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成人畸形手术的晚期并发症和不良事件:事件类型、发生率及信息缺口的叙述性综述

Late Complications and Adverse Events in Adult Deformity Surgery: A Narrative Review of Event Types, Prevalence, and Information Gaps.

作者信息

Berven Sigurd H, Smith Justin S, Street John T, Klineberg Eric, Qiu Yong, Wague Aboubacar, Lewis Stephen J

机构信息

Department of Neurosurgery and Orthopaedic Surgery, University of California San Francisco, Spinal Disorders Service, San Francisco, CA, USA.

Department of Neurosurgery, University of Virginia, Charlottesville, VA, USA.

出版信息

Global Spine J. 2025 Jul;15(3_suppl):159S-171S. doi: 10.1177/21925682251342556. Epub 2025 Jul 9.

Abstract

Study DesignLiterature review.ObjectivesThe purpose of this paper is to provide a narrative review of late complications in adult deformity surgery, including infection, pseudarthrosis and junctional pathology after deformity correction. This review aims to highlight limitations of current management and identify potential areas of improvement and further study.MethodsWe identified common challenges of late complications in adult spinal deformity surgery and performed a directed literature review to summarize the current management and issues encountered in these adverse events. Through consensus, we highlighted the knowledge gaps in the current literature and suggested areas of interest for further study to improve understanding and management of these conditions.ResultsA summary is provided with detailed review of late complications that include infection, pseudarthrosis, junctional pathology, and late decompensation after deformity correction. Important consideration to choosing the appropriate upper and lower instrumented levels, obtaining desired coronal and sagittal alignment, preserving the adjacent ligamentous and muscular structures, obtaining solid arthrodesis, recognizing and optimizing patients for surgery, appropriate pre and post-operative protocols, and appropriately defining normal and pathological parameters.ConclusionsRecognizing appropriate predictor and outcome variables are important for identifying factors, modifiable and fixed, that may be important to make a clinically important difference in outcomes in the surgical treatment of adult spinal deformity. Future studies to reduce late complications are important to improve value and outcome in adult spinal deformity surgery.

摘要

研究设计

文献综述。

目的

本文旨在对成人脊柱畸形手术的晚期并发症进行叙述性综述,包括畸形矫正后的感染、假关节形成和交界区病变。本综述旨在突出当前治疗方法的局限性,并确定潜在的改进和进一步研究领域。

方法

我们确定了成人脊柱畸形手术晚期并发症的常见挑战,并进行了定向文献综述,以总结这些不良事件的当前治疗方法和遇到的问题。通过共识,我们突出了当前文献中的知识空白,并提出了进一步研究的感兴趣领域,以提高对这些情况的理解和管理。

结果

提供了一份总结,详细综述了晚期并发症,包括感染、假关节形成、交界区病变以及畸形矫正后的晚期失代偿。在选择合适的上下固定节段、获得理想的冠状面和矢状面排列、保留相邻的韧带和肌肉结构、实现坚固的融合、识别并优化手术患者、制定合适的术前和术后方案以及恰当定义正常和病理参数方面的重要考虑因素。

结论

识别合适的预测因素和结果变量对于确定可能对成人脊柱畸形手术治疗结果产生临床重要差异的可改变和固定因素很重要。未来减少晚期并发症的研究对于提高成人脊柱畸形手术的价值和结果很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3aa1/12254621/aa2fd2ab3e54/10.1177_21925682251342556-fig1.jpg

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