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成人脊柱畸形手术患者神经并发症的识别与处理

Identification and Management of Neurologic Complications in Patients Undergoing Adult Spinal Deformity Surgery.

作者信息

Nielsen Christopher J, Smith Justin S, Martin Allan R, Rocos Brett, Jentzsch Thorsten, Ravinsky Robert A, Oitment Colby, Pahuta Markian, Kato So, Lewis Stephen J

机构信息

Schroeder Arthritis Institute, Department of Orthopaedic Surgery, Toronto Western Hospital, University of Toronto, University Health Network, Toronto, ON, Canada.

AO Knowledge Forum Deformity, Associate Member, Davos, Switzerland.

出版信息

Global Spine J. 2025 Jul;15(3_suppl):135S-147S. doi: 10.1177/21925682241264221. Epub 2025 Jul 9.

Abstract

Study DesignNarrative Literature Review.ObjectiveTo provide a comprehensive literature review of neurologic complications in Adult Spinal Deformity (ASD) surgery in the pre-operative, peri-operative and post-operative periods.MethodsA broad review of the literature was conducted using the multiple databases including Pubmed, Embase, Scopus and the Cochrane library. Individual studies of relevance were appraised and included at the discretion of the authors on the basis of pertinence, impact on practice and scientific merit.ResultsThe evidence regarding epidemiology, classification of complications, pre-operative evaluation of patients, peri-operative strategies to mitigate risk, intra-operative management of neuromonitoring changes and post-operative management of neurologic injury was critically appraised. Patients with the highest risk of neurologic complication include those with pre-surgery neuroaxis abnormality, high Deformity Angular Ratio, 3 column osteotomies and increased blood loss. Accurate and timely identification of intraoperative neuromonitoring changes is critical to ensuring appropriate response depending on whether changes are perfusion based (maintain adequate MAP and Hb, reverse corrective maneuvers) or traumatic (decompression of neural elements, assessment of instrumentation, reversal of corrective maneuvers, steroids). Surgical checklists can help surgeons navigate these stressful events to ensure appropriate steps and interventions are taken.ConclusionNeurological injuries occurring during the course of ASD surgery are potentially devastating complication, with regards to both patient morbidity and economic impact. Pre-operative identification of high risk patients, perioperative strategies to improve safety, timely recognition and management of intra-operative neuromonitoring changes and post-operative supportive measures can potentially reduce the incidence and significance of neurological injuries.

摘要

研究设计

叙述性文献综述。

目的

对成人脊柱畸形(ASD)手术术前、术中和术后的神经并发症进行全面的文献综述。

方法

使用包括PubMed、Embase、Scopus和Cochrane图书馆在内的多个数据库对文献进行广泛检索。根据相关性、对实践的影响和科学价值,由作者酌情评估并纳入相关的个体研究。

结果

对有关神经并发症的流行病学、并发症分类、患者术前评估、降低风险的围手术期策略、术中神经监测变化的管理以及术后神经损伤的管理等证据进行了批判性评价。神经并发症风险最高的患者包括术前神经轴异常、高畸形角比、三柱截骨术和失血增加的患者。准确及时地识别术中神经监测变化对于根据变化是基于灌注(维持足够的平均动脉压和血红蛋白、逆转矫正操作)还是创伤性(减压神经结构、评估器械、逆转矫正操作、使用类固醇)确保适当反应至关重要。手术检查表可以帮助外科医生应对这些压力事件,以确保采取适当的步骤和干预措施。

结论

ASD手术过程中发生的神经损伤是一种潜在的毁灭性并发症,对患者的发病率和经济影响都很大。术前识别高危患者、围手术期提高安全性的策略、及时识别和处理术中神经监测变化以及术后支持措施可能会降低神经损伤的发生率和严重程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef91/12254560/218625dcf82e/10.1177_21925682241264221-fig1.jpg

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