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脊柱畸形手术中的术中神经监测:方式、优势、局限性及法医学问题——外科医生的观点

Intraoperative neuromonitoring in spine deformity surgery: modalities, advantages, limitations, medicolegal issues - surgeons' views.

作者信息

Biscevic Mirza, Sehic Aida, Krupic Ferid

机构信息

Department of Orthopedics, General Hospital Sarajevo, Bosnia and Herzegovina.

Department of Intraoperative Neurophysiologic Monitoring, SMS, Louisville, Kentucky, USA.

出版信息

EFORT Open Rev. 2020 Jan 29;5(1):9-16. doi: 10.1302/2058-5241.5.180032. eCollection 2020 Jan.

DOI:10.1302/2058-5241.5.180032
PMID:32071769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7017597/
Abstract

In spine deformity surgery, iatrogenic neurologic injuries might occur due to the mechanical force applied to the spinal cord from implants, instruments, and bony structures, or due to ischemic changes from vessel ligation during exposure and cord distraction/compression during corrective manoeuvres.Prompt reaction within the reversible phase (reducing of compressive/distractive forces) usually restores functionality of the spinal cord, but if those forces continue to persist, a permanent neurological deficit might be expected.With monitoring of sensory pathways (dorsal column-medial lemniscus) by somatosensory-evoked potentials (SSEPs), such events are detected with a sensitivity of up to 92%, and a specificity of up to 100%.The monitoring of motor pathways by transcranial electric motor-evoked potentials (TceMEPs) has a sensitivity and a specificity of up to 100%, but it requires avoidance of halogenated anaesthetics and neuromuscular blockades.Different modalities of intraoperative neuromonitoring (IONM: SSEP, TceMEP, or combined) can be performed by the neurophysiologist, the technician or the surgeon. Combined SSEP/TceMEP performed by the neurophysiologist in the operating room is the preferable method of IONM, but it might be impractical or unaffordable in many institutions. Still, many spine deformity surgeries worldwide are performed without any type of IONM. Medicolegal aspects of IONM are different worldwide and in many cases some vagueness remains.The type of IONM that a spinal surgeon employs should be reliable, affordable, practical, and recognized by the medicolegal guidelines. Cite this article: 2020;5:9-16. DOI: 10.1302/2058-5241.5.180032.

摘要

在脊柱畸形手术中,医源性神经损伤可能由于植入物、器械和骨质结构对脊髓施加的机械力而发生,也可能由于暴露期间血管结扎导致的缺血性改变以及矫正操作期间脊髓牵张/压迫而发生。在可逆阶段迅速做出反应(减轻压迫/牵张力量)通常可恢复脊髓功能,但如果这些力量持续存在,则可能会出现永久性神经功能缺损。通过体感诱发电位(SSEP)监测感觉通路(背柱-内侧丘系),此类事件的检测灵敏度高达92%,特异性高达100%。通过经颅电动运动诱发电位(TceMEP)监测运动通路的灵敏度和特异性高达100%,但需要避免使用卤化麻醉剂和神经肌肉阻滞剂。术中神经监测(IONM:SSEP、TceMEP或联合使用)的不同模式可由神经生理学家、技术人员或外科医生进行。由神经生理学家在手术室进行的联合SSEP/TceMEP是IONM的首选方法,但在许多机构可能不实用或费用过高。尽管如此,全球仍有许多脊柱畸形手术在没有任何类型IONM的情况下进行。IONM的法医学方面在全球各地有所不同,在许多情况下仍存在一些模糊之处。脊柱外科医生采用的IONM类型应可靠、经济实惠、实用,并得到法医学指南的认可。引用本文:2020;5:9 - 16。DOI:10.1302/2058 - 5241.5.180032。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29a0/7017597/b0298772d114/eor-5-9-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29a0/7017597/258fe0303a47/eor-5-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29a0/7017597/cac3419e7e9d/eor-5-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29a0/7017597/b0298772d114/eor-5-9-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29a0/7017597/258fe0303a47/eor-5-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29a0/7017597/cac3419e7e9d/eor-5-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29a0/7017597/b0298772d114/eor-5-9-g003.jpg

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