眼内炎的早期玻璃体切除术：视力结果与并发症发生率
Early Vitrectomy in Endophthalmitis: Visual Outcomes and Complication Rates.
作者信息
Sromicki Julian W, Stahel Marc, Blum Robert A, Rudolph Katrin A, Barthelmes Daniel
机构信息
Department of Ophthalmology, University Hospital and University of Zurich, Frauenklinikstrasse 24, 8091, Zurich, Switzerland.
Save Sight Institute, The University of Sydney, Sydney, Australia.
出版信息
Ophthalmol Ther. 2025 Aug;14(8):2031-2042. doi: 10.1007/s40123-025-01196-x. Epub 2025 Jul 9.
INTRODUCTION
This study examined visual outcomes and complication rates after early pars plana vitrectomy (PPV) in eyes with endophthalmitis.
METHODS
The study was designed as a single-center, retrospective, observational database study. A total of 92 eyes treated with early PPV for endophthalmitis at the University Hospital Zurich between 2006 and 2016 were included. Endophthalmitis cases following cataract surgery (CAT, n = 44), intravitreal injection (IVI, n = 12), trabeculectomy (TRAB, n = 6), and Others (e.g., trauma or endogenous, n = 30) were assessed. Visual acuity (VA) and intraocular pressure (IOP) from prior to endophthalmitis to 12 months after PPV were analyzed. Secondary outcomes included complications following the procedure.
RESULTS
CAT and IVI groups showed good visual outcomes. Final VA in CAT and IVI groups was not statistically different to prior to endophthalmitis (CAT p = 0.840, IVI p = 0.933). In the CAT group, 78.9% of eyes with a starting VA of > light perception achieved ≥ 20/40 final VA. The highest rate of patients with at least one complication was observed in TRAB (100%), followed by Others (63.3%), IVI (50.0%), and CAT groups (40.9%).
CONCLUSION
Early PPV may be beneficial in endophthalmitis following cataract surgery and intravitreal injection, regardless of initial VA.
引言
本研究探讨了眼内炎患者早期玻璃体切割术（PPV）后的视力结果和并发症发生率。
方法
本研究设计为单中心、回顾性、观察性数据库研究。纳入了2006年至2016年间在苏黎世大学医院接受早期PPV治疗眼内炎的92只眼。评估了白内障手术（CAT，n = 44）、玻璃体内注射（IVI，n = 12）、小梁切除术（TRAB，n = 6）及其他情况（如外伤或内源性感染，n = 30）后的眼内炎病例。分析了从眼内炎发生前至PPV后12个月的视力（VA）和眼压（IOP）。次要结果包括手术后的并发症。
结果
CAT组和IVI组显示出良好的视力结果。CAT组和IVI组的最终视力与眼内炎发生前相比无统计学差异（CAT组p = 0.840，IVI组p = 0.933）。在CAT组中，起始视力>光感的眼中，78.9%的最终视力≥20/40。观察到至少有1种并发症的患者比例最高的是TRAB组（100%），其次是其他情况组（63.3%）、IVI组（50.0%）和CAT组（40.9%）。
结论
早期PPV可能对白内障手术和玻璃体内注射后发生的眼内炎有益，无论初始视力如何。
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