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马盲肠丙酸的糖异生作用。

Gluconeogenesis from caecal propionate in the horse.

作者信息

Ford E J, Simmons H A

出版信息

Br J Nutr. 1985 Jan;53(1):55-60. doi: 10.1079/bjn19850010.

DOI:10.1079/bjn19850010
PMID:4063263
Abstract

The production of propionate in the caecum of the horse has been measured in two Shetland-type ponies fitted with caecal and colonic cannulas and fed on hay or on hay and wheat bran. A continuous intracaecal infusion of 14C-labelled sodium propionate was used and samples were obtained from a cannula at the origin of the right ventral colon. A simultaneous intravenous infusion of [2-3H]glucose was used to measure total glucose entry. On a hay diet which provided 177 kJ/kg body-weight per d, mean caecal propionate production was 19.6 (range 17.2-21.2) mg/h per kg body-weight and on a hay and wheat bran diet, which provided 187 kJ/kg body-weight per d, mean caecal propionate production was 34.0 (range 28.9-38.3) mg/h per kg body-weight. Mean total glucose production (mg/h per kg body-weight) in one pony was 104 (range 100-110) and in the other 135 (range 123-153). Rates were not influenced by diet. About 7% of total glucose production was derived from propionate produced in the caecum and this percentage was unaffected by diet or by individual animals.

摘要

在两只装有盲肠和结肠插管的设得兰型小马身上,测量了它们在以干草或干草加麦麸为食时盲肠中丙酸的生成量。采用连续向盲肠内输注14C标记的丙酸钠的方法,并从右腹侧结肠起始处的插管采集样本。同时静脉输注[2-3H]葡萄糖以测量葡萄糖的总进入量。在每日提供177千焦/千克体重的干草日粮中,每千克体重的平均盲肠丙酸生成量为19.6(范围17.2 - 21.2)毫克/小时;在每日提供187千焦/千克体重的干草加麦麸日粮中,每千克体重的平均盲肠丙酸生成量为34.0(范围28.9 - 38.3)毫克/小时。一匹小马的平均总葡萄糖生成量(每千克体重毫克/小时)为104(范围100 - 110),另一匹为135(范围123 - 153)。生成速率不受日粮影响。约7%的总葡萄糖生成量来自盲肠中产生的丙酸,且这一比例不受日粮或个体动物的影响。

相似文献

1
Gluconeogenesis from caecal propionate in the horse.马盲肠丙酸的糖异生作用。
Br J Nutr. 1985 Jan;53(1):55-60. doi: 10.1079/bjn19850010.
2
Gluconeogenesis from propionate produced in the colon of the horse.源自马结肠中产生的丙酸的糖异生作用。
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Liquid flow and capacity of the caecum and colon of the horse.马的盲肠和结肠的液体流动及容量
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