• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Endothelial Glycocalyx Integrity as a Prognostic Key in Sepsis: New Insights from the CLOVERS Trial.

作者信息

Fernández-Sarmiento Jaime

机构信息

Department of Pediatrics and Intensive Care, Universidad de La Sabana, Chía, Colombia; and.

Department of Pediatrics and Intensive Care, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia.

出版信息

Ann Am Thorac Soc. 2025 Sep;22(9):1303-1304. doi: 10.1513/AnnalsATS.202506-692ED.

DOI:10.1513/AnnalsATS.202506-692ED
PMID:40632891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12416306/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eed/12416306/7a9adb782e0d/AnnalsATS.202506-692EDUf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eed/12416306/7a9adb782e0d/AnnalsATS.202506-692EDUf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6eed/12416306/7a9adb782e0d/AnnalsATS.202506-692EDUf1.jpg

相似文献

1
Endothelial Glycocalyx Integrity as a Prognostic Key in Sepsis: New Insights from the CLOVERS Trial.内皮糖萼完整性作为脓毒症预后的关键因素：CLOVERS试验的新见解
Ann Am Thorac Soc. 2025 Sep;22(9):1303-1304. doi: 10.1513/AnnalsATS.202506-692ED.
2
Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial.脓毒症中内皮糖萼降解：晶体液宽松或血管升压药早期复苏治疗脓毒症（CLOVERS）试验分析，一项多中心、3期、随机试验
Ann Am Thorac Soc. 2025 Sep;22(9):1382-1393. doi: 10.1513/AnnalsATS.202501-012OC.
3
Liposomal nanocarriers of preassembled glycocalyx restore normal venular permeability and shear stress sensitivity in sepsis: assessed quantitatively with a novel microchamber system.预先组装的糖萼的脂质体纳米载体恢复脓毒症中正常的小静脉通透性和切应力敏感性：用新型微室系统定量评估。
Am J Physiol Heart Circ Physiol. 2024 Aug 1;327(2):H390-H398. doi: 10.1152/ajpheart.00138.2024. Epub 2024 Jun 14.
4
[Clinical study on the effect of glycosaminoglycans on vascular endothelial glycocalyx in sepsis].[糖胺聚糖对脓毒症血管内皮糖萼影响的临床研究]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2025 Jun;37(6):527-534. doi: 10.3760/cma.j.cn121430-20240725-00634.
5
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement.管腔血管功能障碍促使高血糖性卒中时血脑屏障快速损伤：管腔糖萼和补体的关键作用
bioRxiv. 2025 Jun 28:2025.06.26.661858. doi: 10.1101/2025.06.26.661858.
6
Therapeutic strategies targeting the endothelial glycocalyx.靶向内皮糖萼的治疗策略。
Curr Opin Clin Nutr Metab Care. 2023 Nov 1;26(6):543-550. doi: 10.1097/MCO.0000000000000973. Epub 2023 Aug 9.
7
Time course and contributors to greater glycocalyx thickness and integrity following Western diet consumption.西方饮食摄入后糖萼厚度增加及完整性提高的时间进程和影响因素。
Am J Physiol Heart Circ Physiol. 2025 Sep 1;329(3):H765-H773. doi: 10.1152/ajpheart.00491.2025. Epub 2025 Aug 18.
8
ENDOTHELIAL GLYCOCALYX SHEDDING IN INTRA-ABDOMINAL SEPSIS: A FEASIBILITY STUDY.腹腔脓毒症中内皮糖萼脱落：一项可行性研究。
Shock. 2023 Apr 1;59(4):540-546. doi: 10.1097/SHK.0000000000002079. Epub 2023 Jan 10.
9
Endothelial Glycocalyx Degradation Patterns in Sepsis-Associated Pediatric Acute Respiratory Distress Syndrome: A Single Center Retrospective Observational Study.脓毒症相关小儿急性呼吸窘迫综合征中内皮糖萼降解模式：一项单中心回顾性观察研究
J Intensive Care Med. 2024 Mar;39(3):277-287. doi: 10.1177/08850666231200162. Epub 2023 Sep 6.
10
Peripheral Vasopressor Use in Early Sepsis-Induced Hypotension.外周血管升压药在早期脓毒症诱导的低血压中的应用
JAMA Netw Open. 2025 Aug 1;8(8):e2529148. doi: 10.1001/jamanetworkopen.2025.29148.

本文引用的文献

1
Hyperprocalcitonemia and Endothelial and Microcirculatory Dysfunction in Children With Sepsis and Septic Shock: Single-Center Observational Cohort Study in Colombia, 2021-2024.脓毒症和脓毒性休克患儿的高降钙素原血症与内皮及微循环功能障碍：2021 - 2024年在哥伦比亚进行的单中心观察性队列研究
Pediatr Crit Care Med. 2025 Aug 1;26(8):e1024-e1033. doi: 10.1097/PCC.0000000000003782. Epub 2025 Jun 25.
2
Advancing Microcirculatory Therapies in Pediatric Sepsis: Current Opportunities and Future Directions.推进小儿脓毒症的微循环治疗：当前机遇与未来方向
J Intensive Care Med. 2025 May 29:8850666251340601. doi: 10.1177/08850666251340601.
3
Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial.
脓毒症中内皮糖萼降解：晶体液宽松或血管升压药早期复苏治疗脓毒症（CLOVERS）试验分析，一项多中心、3期、随机试验
Ann Am Thorac Soc. 2025 Sep;22(9):1382-1393. doi: 10.1513/AnnalsATS.202501-012OC.
4
Endothelial Glycocalyx Turnover in Vascular Health and Disease: Rethinking Endothelial Dysfunction.血管健康与疾病中的内皮糖萼周转：重新审视内皮功能障碍
Annu Rev Biochem. 2025 Jun;94(1):561-586. doi: 10.1146/annurev-biochem-032620-104745. Epub 2025 Mar 25.
5
Syndecan-1: a key player in health and disease.Syndecan-1：健康与疾病中的关键角色。
Immunogenetics. 2024 Dec 17;77(1):9. doi: 10.1007/s00251-024-01366-4.
6
Definition and Epidemiology of Sepsis.脓毒症的定义和流行病学。
Semin Respir Crit Care Med. 2024 Aug;45(4):461-468. doi: 10.1055/s-0044-1787990. Epub 2024 Jul 5.
7
Managing sepsis and septic shock in an endothelial glycocalyx-friendly way: from the viewpoint of surviving sepsis campaign guidelines.以内皮糖萼友好的方式管理脓毒症和感染性休克：从拯救脓毒症运动指南的角度来看
Ann Intensive Care. 2024 Apr 24;14(1):64. doi: 10.1186/s13613-024-01301-6.
8
The pathophysiology of sepsis and precision-medicine-based immunotherapy.脓毒症的病理生理学与基于精准医学的免疫治疗。
Nat Immunol. 2024 Jan;25(1):19-28. doi: 10.1038/s41590-023-01660-5. Epub 2024 Jan 2.
9
Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis.复苏相关内皮病（RAsE）：基于系统评价和荟萃分析的概念框架。
Syst Rev. 2023 Nov 22;12(1):221. doi: 10.1186/s13643-023-02385-0.
10
Endothelial and Glycocalyx Biomarkers in Children With Sepsis After One Bolus of Unbalanced or Balanced Crystalloids.失衡或平衡晶体液单次冲击后脓毒症儿童的内皮和糖萼生物标志物。
Pediatr Crit Care Med. 2023 Mar 1;24(3):213-221. doi: 10.1097/PCC.0000000000003123. Epub 2023 Jan 4.