Dhanoa M S, Siddons R C, France J, Gale D L
Br J Nutr. 1985 May;53(3):663-71. doi: 10.1079/bjn19850076.
A multicompartmental model, which assumes first-order kinetics, is proposed to describe digesta flow along the gastrointestinal tract of ruminants. Solution of the model yields a multiplicative equation, containing a single-exponential term and a double-exponential term, for describing faecal outflow rate. The logarithmic transformation of the equation was fitted to eighty-two excretion curves obtained after the administration of marker into the rumen of cattle and sheep, and compared with other published models. It was found to be superior to the other models in that it fitted all the data sets successfully.
提出了一个假设为一级动力学的多隔室模型,用于描述反刍动物胃肠道内食糜的流动。该模型的解产生了一个乘法方程,其中包含一个单指数项和一个双指数项,用于描述粪便流出率。将该方程的对数变换拟合到向牛和羊瘤胃中投放标记物后获得的82条排泄曲线,并与其他已发表的模型进行比较。结果发现它优于其他模型,因为它成功地拟合了所有数据集。