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[Fluorescence of Tb3 complexes with metaphase chromosomes of mink fibroblasts].

作者信息

Beliaev N D, Budker V G, Dubrovskaia V A, Shilov A G

出版信息

Biokhimiia. 1985 Nov;50(11):1782-5.

PMID:4063402
Abstract

The fluorescence of the Tb3+ complex with metaphase chromosomes of mink fibroblasts was studied. It was shown that the fluorescence intensity of this complex is 6.5 times as high as that of the Tb3+-native DNA complex. The fluorescence of the chromosome-Tb3+ complex is predominantly determined by chromosomal DNA. The high intensity of fluorescence may be due to partial disturbances in the secondary structure of DNA during folding of the metaphasic chromosome.

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