El-Sawy N A, Fathi A M, Ali S K, Abdelrheem D A, Hegab M M, El-Deeb M M
Chemistry Department of Medicinal and Aromatic Plants, Research Institute of Medicinal and Aromatic Plants, Beni-Suef University, Beni-Suef, Beni-Suef, 62514, Egypt.
Physical Chemistry Department, National Research Centre, 33 El Bohoth St. (El-Tahrir St. Former), P.O.12622, Dokki, Giza, Egypt.
Sci Rep. 2025 Jul 9;15(1):24626. doi: 10.1038/s41598-025-08585-z.
Methanolic extraction (ME) of terminalia bentzoe leaves and its aqueous (QF) and n-butanol (nBF) fractions are investigated as sustainable green compounds for both anticorrosion and antimicrobial activity. Extracted and fractionated phytochemicals and their functional groups are detected by GC-MS and FTIR. According to the electrochemical results, ME, QF and nBF samples are considered as anodic inhibitors that mainly inhibit the anodic dissolution of copper (Cu) in 0.6 M NaCl solution. Their inhibition efficiencies increase by increasing their concentrations up to 60 ppm, and the highest value of inhibition efficiency is found to be 94.4% for nBF. The presence of the protective adsorbed layer from the extracted and fractionated phytochemical compounds onto the Cu surface was supported by FESEM analyses and theoretical. On the other hand, exploring the antimicrobial activity of ME, QF and nBF samples against Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Escherichia coli, Salmonella typhi, Shigella boydii, Aspergillus niger and Candida albicans was made by using modified Kirby-Bauer disc diffusion technique. Data indicated good resistance against a variety of bacterial infections for the studied green compounds.
对诃子叶的甲醇提取物（ME）及其水相（QF）和正丁醇相（nBF）馏分作为具有防腐和抗菌活性的可持续绿色化合物进行了研究。通过气相色谱 - 质谱联用仪（GC-MS）和傅里叶变换红外光谱仪（FTIR）检测提取和分离得到的植物化学物质及其官能团。根据电化学结果，ME、QF和nBF样品被认为是阳极抑制剂，主要抑制铜（Cu）在0.6 M氯化钠溶液中的阳极溶解。它们的抑制效率随着浓度增加至60 ppm而提高，nBF的抑制效率最高值为94.4%。场发射扫描电子显微镜（FESEM）分析和理论研究支持了从提取和分离得到的植物化学化合物在铜表面形成保护性吸附层的观点。另一方面，采用改良的 Kirby-Bauer 纸片扩散技术研究了ME、QF和nBF样品对金黄色葡萄球菌、蜡样芽孢杆菌、单核细胞增生李斯特菌、大肠杆菌、伤寒沙门氏菌、鲍氏志贺菌、黑曲霉和白色念珠菌的抗菌活性。数据表明，所研究的绿色化合物对多种细菌感染具有良好的抗性。
