Das Gitishree, Kim Do-Yeong, Fan Chen, Gutiérrez-Grijalva Erick P, Heredia J Basilio, Nissapatorn Veeranoot, Mitsuwan Watcharapong, Pereira Maria Lourdes, Nawaz Muhammad, Siyadatpanah Abolghasem, Norouzi Roghayeh, Sawicka Barbara, Shin Han-Seung, Patra Jayanta Kumar
Research Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, Goyangsi, South Korea.
Skin Research Institute of Singapore, Agency for Science, Technology and Research, A∗STAR, Singapore, Singapore.
Front Pharmacol. 2020 Oct 8;11:561248. doi: 10.3389/fphar.2020.561248. eCollection 2020.
The evaluation and confirmation of healing properties of several plant species of genus based on their traditional uses and the clinical claims are of utmost importance. Genus has received more attention to assess and validate the therapeutic potential and clinical approval due to its immense folk medicinal and traditional applications. Various species of genus are used in the form of herbal medicine and formulations, in treatment of diseases, including headache, fever, pneumonia, flu, geriatric, cancer, to improve memory, abdominal and back pain, cough and cold, conjunctivitis, diarrhea, heart disorder, leprosy, sexually transmitted diseases, and urinary tract disorders. These are reported to possess numerous biological properties, counting: antibacterial, antifungal, antiinflammatory, antiviral, antiretroviral, antioxidant, and antipa7rasitic. This current research review aims to update the detailed biological activities, pre-clinical and clinical studies of various extracts and secondary metabolites from several plant species under the genus , along with information on the traditional uses and chemical composition to develop a promising strategy for their potential applications in the form of medicine or use in modern drug formulations for treating diseases like pneumonia, flu, and other types of viral infections or controlling human contagions.
基于几种该属植物的传统用途和临床宣称来评估和确认其愈合特性至关重要。由于该属植物在民间医学和传统应用方面极为广泛，因此在评估和验证其治疗潜力以及临床认可度方面受到了更多关注。该属的各种植物以草药和配方的形式用于治疗多种疾病，包括头痛、发烧、肺炎、流感、老年病、癌症、改善记忆力、腹痛和背痛、咳嗽和感冒、结膜炎、腹泻、心脏病、麻风病、性传播疾病以及泌尿系统疾病。据报道，这些植物具有多种生物学特性，包括：抗菌、抗真菌、抗炎、抗病毒、抗逆转录病毒、抗氧化和抗寄生虫。本研究综述旨在更新该属几种植物的各种提取物和次生代谢产物的详细生物学活性、临床前和临床研究，以及传统用途和化学成分信息，以便制定一个有前景的策略，将其开发成药物形式或用于现代药物配方，以治疗肺炎、流感和其他类型的病毒感染或控制人类传染病。
