白内障术后并发视网膜中央静脉阻塞（CRVO）：一例病例报告及多因素分析
Central Retinal Vein Occlusion (CRVO) complicating post-cataract surgery: a case report and multifactorial analysis.
作者信息
Xiaodong Li, Xin Liu, Xuewei Qin, Mei Chen, Xianfeng Yao
机构信息
The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, China.
出版信息
BMC Ophthalmol. 2025 Jul 9;25(1):402. doi: 10.1186/s12886-025-04241-2.
BACKGROUND
Central retinal vein occlusion (CRVO) is a rare but severe complication following cataract surgery. This report highlights a unique case of CRVO secondary to phacoemulsification in a patient with multiple comorbidities.
CASE PRESENTATION
A 60-year-old female presented with left-eye blurred vision, photophobia, and elevated intraocular pressure. Preoperative findings included neovascular glaucoma, nuclear cataract, and suspected retinitis pigmentosa. Postoperatively, she developed CRVO with flame-shaped retinal hemorrhages, confirmed via fundoscopy and optical coherence tomography (OCT). Laboratory tests revealed hypertriglyceridemia (3× normal).
CONCLUSION
This case underscores the synergistic roles of vascular pathology (neovascular glaucoma), surgical stress (IOP fluctuations), and metabolic dysfunction (hypertriglyceridemia) in CRVO pathogenesis. Perioperative monitoring of blood rheology and targeted interventions (e.g., anti-VEGF therapy) may mitigate risks in high-risk patients.
背景
视网膜中央静脉阻塞（CRVO）是白内障手术后一种罕见但严重的并发症。本报告重点介绍了一例在患有多种合并症的患者中，因超声乳化白内障吸除术继发CRVO的独特病例。
病例介绍
一名60岁女性出现左眼视力模糊、畏光和眼压升高。术前检查发现新生血管性青光眼、核性白内障和疑似视网膜色素变性。术后，通过眼底镜检查和光学相干断层扫描（OCT）确诊她发生了伴有火焰状视网膜出血的CRVO。实验室检查显示高甘油三酯血症（3倍于正常水平）。
结论
该病例强调了血管病变（新生血管性青光眼）、手术应激（眼压波动）和代谢功能障碍（高甘油三酯血症）在CRVO发病机制中的协同作用。围手术期监测血液流变学并采取针对性干预措施（如抗VEGF治疗）可能会降低高危患者的风险。
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