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[血糖浓度变化对兔眼静息电位的影响]

[Effect of changes in blood glucose concentration on the standing potential of the rabbit eye].

作者信息

Mironova E M, Byzov A L

出版信息

Biull Eksp Biol Med. 1985 Nov;100(11):530-2.

PMID:4063493
Abstract

The paper deals with the study of the influence of changes of glucose blood concentration in rabbits on the standing potential of the eye, which reflects the functioning of the retinal pigment epithelium and photoreceptors. Recordings of the electrooculogram (EOG), determination of glucose blood level and ophthalmoscopic and histological examinations of the eye were performed in 48 rabbits. Short-term increase of glucose concentration was accompanied by the increase in the standing potential and Arden EOG ratio, with hypoglycemia evoking the opposite effect. A long-term (4 month) hyperglycemia was accompanied by the reversible decrease of both parameters studied. No ophthalmoscopic and histological changes were observed.

摘要

本文研究了家兔血糖浓度变化对眼静息电位的影响,眼静息电位反映视网膜色素上皮和光感受器的功能。对48只家兔进行了眼电图(EOG)记录、血糖水平测定以及眼部的检眼镜和组织学检查。血糖浓度短期升高伴随着静息电位和Arden EOG比值的增加,而低血糖则产生相反的效果。长期(4个月)高血糖伴随着所研究的两个参数的可逆性降低。未观察到检眼镜和组织学变化。

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