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走完最后一公里——将证据带给以色列的个人:关于实施科学能力建设的评论

Travelling the Last Mile - Bringing Evidence to Individuals in Israel : a commentary on building capacity in implementation science.

作者信息

Mukamal Kenneth J, Keinan-Boker Lital

机构信息

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Faculty of Social Welfare & Health Sciences, School of Public Health, University of Haifa, Haifa, Israel.

出版信息

Isr J Health Policy Res. 2025 Jul 10;14(1):42. doi: 10.1186/s13584-025-00705-4.

DOI:10.1186/s13584-025-00705-4
PMID:40635099
Abstract

In their previously published article in the Israel Journal of Health Policy Research, Rose and colleagues describe and advocate for greater use of implementation science in Israel. As a discipline, implementation science seeks to traverse the last steps in bringing new science from research to clinical practice, which are often the most difficult of the entire process. Implementation science in general faces substantial challenges, including the extraordinary heterogeneity of the dissemination process, and the obstacles represented by established practices, singular preferences, and questions about generalizability. In our view, implementation science complements classic epidemiology as part of a continuum of population health research that warrants greater attention and funding. For now, however, implementation science will need to show that it can consistently achieve sizable, durable, and widespread results if it is to traverse its own last mile and establish itself as a successful and permanent component of biomedicine in Israel.

摘要

罗斯及其同事在他们之前发表于《以色列卫生政策研究杂志》的文章中,描述并倡导在以色列更多地运用实施科学。作为一门学科,实施科学旨在跨越将新科学从研究转化为临床实践的最后几步,而这几步往往是整个过程中最困难的。总体而言,实施科学面临着重大挑战,包括传播过程的异质性极高,以及既定实践、个人偏好和关于可推广性的问题所带来的障碍。我们认为,实施科学作为人群健康研究连续统一体的一部分,对经典流行病学起到补充作用,值得更多关注和资金投入。然而目前,如果实施科学想要跨越自身的最后阶段并在以色列确立为生物医学成功且持久的组成部分,就需要证明它能够持续取得可观、持久且广泛的成果。

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本文引用的文献

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Isr J Health Policy Res. 2025 Apr 2;14(1):4. doi: 10.1186/s13584-025-00669-5.
2
Predictive Models to Assess Risk of Persistent Opioid Use, Opioid Use Disorder, and Overdose.评估持续使用阿片类药物、阿片类药物使用障碍和过量用药风险的预测模型。
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Implementation Strategies to Improve Blood Pressure Control in the United States: A Scientific Statement From the American Heart Association and American Medical Association.
提高美国血压控制水平的实施策略:美国心脏协会和美国医学协会的科学声明。
Hypertension. 2023 Oct;80(10):e143-e157. doi: 10.1161/HYP.0000000000000232. Epub 2023 Aug 31.
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Effectiveness of BNT162b2 Vaccine against Omicron Variant Infection among Children 5-11 Years of Age, Israel.BNT162b2 疫苗对 5-11 岁儿童感染奥密克戎变异株的有效性,以色列。
Emerg Infect Dis. 2023 Apr;29(4):771-777. doi: 10.3201/eid2904.221285. Epub 2023 Mar 2.
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Trends in Blood Pressure Treatment Intensification in Older Adults With Hypertension in the United States, 2008 to 2018.美国高血压老年患者血压治疗强化趋势,2008 年至 2018 年。
Hypertension. 2023 Mar;80(3):553-562. doi: 10.1161/HYPERTENSIONAHA.122.19882. Epub 2022 Sep 16.
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Generalizability of Clinical Trials Supporting the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline.支持 2017 年美国心脏病学会/美国心脏协会血压指南的临床试验的可推广性。
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