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虫媒病毒在来自非洲爪蟾(非洲爪蟾)的连续细胞系(XTC-2)中的细胞病变效应和蚀斑形成。

Cytopathic effect and plaque formation by arboviruses in a continuous cell line (XTC-2) from the toad Xenopus laevis.

作者信息

Leake C J, Varma M G, Pudney M

出版信息

J Gen Virol. 1977 May;35(2):335-9. doi: 10.1099/0022-1317-35-2-335.

DOI:10.1099/0022-1317-35-2-335
PMID:406357
Abstract

Forty-six arboviruses were tested for c.p.e. and/or plaque formation in an amphibian cell line. C.p.e. was observed with a high proportion of the viruses tested. Comparative plaque assay, in the XTC-2 cells at 28 degrees C and Vero cells at 37 degrees C, suggests that these systems are comparable in sensitivity and susceptibility to infection. Practical uses of this cell line are discussed.

摘要

对46种虫媒病毒进行了检测,观察其在一种两栖类细胞系中的细胞病变效应(CPE)和/或蚀斑形成情况。在所检测的大部分病毒中均观察到了细胞病变效应。在28℃的XTC - 2细胞和37℃的Vero细胞中进行的比较蚀斑试验表明,这些系统在感染敏感性方面具有可比性。本文还讨论了该细胞系的实际用途。

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