Dineshkumar Thayalan, Rameshkumar Annasamy, Rajkumar Krishnan, Ravindran Swaathi
Department of Oral Pathology and Microbiology, SRM Institute of Science and Technology, SRM Dental College, Ramapuram Campus, Chennai, Tamil Nadu, India.
J Microsc Ultrastruct. 2024 Feb 21;13(2):99-103. doi: 10.4103/jmau.jmau_100_23. eCollection 2025 Apr-Jun.
Formerly believed to be a subtype of odontogenic keratocyst (OKC), orthokeratinized odontogenic cyst (OOC), a rare developing odontogenic cyst, is now believed to be distinct. The clinical, radiographic, histological data are included in this report, along with a review of the literature to aid in comprehending the cyst. A retrospective search in the oral pathology department between 2018 and 2022 was conducted to recover all cases reported as OOC in SRM Dental College, Ramapuram. Radiographs and Haematoxylin and Eosin stained histological slides were re-examined. Overall, there were nine cases in which men were engaged in 80% of the instances and the group's ages varied from 20 to 35. The primary symptoms of all of the patients were pain and edema. The vast majority of cases had an impacted tooth in the jaw. All of the lesions showed clearly visible radiolucency on orthopantomographs [OPG], with the exception of one specific case. Additionally, histological examination of each patient revealed the characteristic microscopic traits and enucleation was done to treat all the cases. OOC has a more favourable outcome than OKC due to variations in prognosis, management and must be considered distinct from OKC. Most of our cases-a large majority-involved adolescent males' mandibles and involved pain and edema. Most were unilocular and all were radiolucent. The literature-recommended histopathological findings were present and all cases were enucleated.
正角化牙源性囊肿（OOC）曾被认为是牙源性角化囊肿（OKC）的一种亚型，它是一种罕见的发育性牙源性囊肿，现在被认为是不同的。本报告包括临床、影像学和组织学数据，并对文献进行综述以帮助理解该囊肿。对2018年至2022年期间口腔病理科进行回顾性检索，以找出拉马普拉姆SRM牙科学院报告为OOC的所有病例。重新检查了X光片和苏木精-伊红染色的组织学切片。总体而言，共有9例病例，其中男性占80%，年龄在20至35岁之间。所有患者的主要症状是疼痛和水肿。绝大多数病例在下颌有一颗阻生牙。除一个特定病例外，所有病变在曲面体层片（OPG）上均显示出明显的透射区。此外，对每位患者的组织学检查均显示出特征性的微观特征，并对所有病例进行了摘除术。由于预后和治疗方法的差异，OOC的预后比OKC更有利，必须将其与OKC区分开来。我们的大多数病例——绝大多数——涉及青少年男性的下颌骨，伴有疼痛和水肿。大多数为单房性，均为透射性。呈现了文献推荐的组织病理学结果，所有病例均进行了摘除术。
